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中药物质基础整体特征的精细表达与解析──中药指纹图谱的研究 被引量:15

Fine expression and analysis of total chemical characteristics of material foundation of Traditional Chinese Herbal Medicines
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摘要 利用近年来发展起来的新分析技术,探索可行的中药质量控制方法,是我国中药现代化研究的一个重要内容。本文以反映中药的整体化学特征为立论依据,在已经应用1HNMR、HPLC、IR、UV等技术进行中药指纹图谱研究的经验和基础上,进一步提出用植物化学的研究方法研究建立规范化的中药特征性总成分获取程序,并完成对中药整体化学特征进行精细表达的方法学研究,为最终建立能反映中药的整体化学特征和中药多组分、多靶点特点的中药质量控制方法提供理论和实验依据。 It is an important part in the studies of the modernization of traditional Chinese medicines(TCMs)to develop applicable methods for the quality control of TCMs with new analytical techniques established in recent years.In this paper,a subject is proposed on the argument of how to express the total chemical characteristics of the material foundation of traditional Chinese herbal medicines(TCHMs),and according to the experience and on the basis of the application of such techniques as IHNMR,HPLC,IR and UV to establish the fingerprints of TCMs it is further proposed to establish a procedure with the method of phytochemical research for acquiring the standard and characteristic general constituents of TCMs,and to accomplish the study of the methodology for the fine expression of the total Chemical characteristics of TCMs so as to provide theoretical and experimental bases for the establishment of a method for the control of TCMs quality,which is able to demonstrate the total chemical characteristics as well as the features of multi-constituents and many targets of TCMs.
作者 秦海林
机构地区 中国医学科学院
出处 《世界科学技术-中药现代化》 2002年第4期12-16,79,共5页 World Science and Technology(Modernization of Traditional Chinese Medicine)
关键词 植物中药 整体化学特征 指纹图谱 中药 质量控制 traditional chinese herbal medicines,total chemical characteristics,fingerprint
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