摘要
目的 研究老年原发性高血压 (EH)合并微量白蛋白尿 (MAU)患者的胰岛素水平及胰岛素敏感性指数的变化。方法 选择不伴有糖尿病及原发性肾脏疾病的老年EH患者 60例 ,所有病人按是否合并微量白蛋白尿 ,将其分为MAU组和正常MAU组 ,测定空腹血糖 (FBG)、胰岛素 (FINS)、血脂、胰岛素敏感性指数 (ISI) ,并进行分析。结果 老年EH患者合并MAU患者伴有高胰岛素血症 ,ISI显著低于不合并MAU患者 (P <0 .0 5)。
Objective\ To investigate the changes of serum insulin and insulin sensitivity index in aged hypertensives with microalbuminuria.Methods\ 60 aged herpertensives without diabetes and primary kidney disease were included in this study.The patients with or without MAU were divided into two groups:MAU group and NMAU group.The important index of fasting blood glucose (FBG)\,insulin (FINS)\,serum lipid were determined and the insulin index (ISI) was calculated at the same time.Results\ The insulin level in aged hypertensives with microalbuminuria was higher than the control group,insulin sensitivity index was siginificantly lower in the patients with microalbuminuria than in those without microalbuminuria (P<0.05).Conclusion\ These results indicate that the aged hypertensives with microalbuminuria are associated with hyperinsulinemia and inslin resistance.
出处
《医师进修杂志》
北大核心
2002年第9期15-16,共2页
Journal of Postgraduates of Medicine
