摘要
目前用fMRI进行脑功能研究的主要依据是血流敏感性[1 ] 和BOLD[2 ] (bloodoxygenation leveldepen dent)对比度增强原理。当某一脑区被激活时 ,由于血流增加 ,引起了氧合血红蛋白浓度的瞬态增加 ,导致磁化率加权脉冲序列中MR信号的增强。本文着重讨论了反卷积方法在脑激活定位中的应用。该法可以有效地提供良好的解剖学定位 。
At present, the main basis of brain function research using fMRI is blood flow sensitivity and principle of contrast enhancement of BOLD(blood oxygenation level dependent). When activating a brain area, due to blood flow increase. There was transient increase of concentration of oxy hemoglobin, causing enhancement of MR signals in magnetic susceptibility weighted pulse series. We mainly focus on discussion of the application of inverse convolution method for the brain activation location. This method could provide good anatomia location effectively so as to lay foundation for comparison and analysis of tested images, or for study of mechanism of several general brain activities to be tested.
出处
《北京生物医学工程》
2002年第3期169-170,共2页
Beijing Biomedical Engineering
