摘要
目的:探讨外周血造血干细胞(PBSC)动员和采集对无血缘关系造血干细胞供者的影响和相关的护理措施。方法:对55例PBSC无关供者采用重组人粒细胞集落刺激因子(rhG-CSF)皮下注射3~5 d,使用CS-3000 p lus型血细胞分离机采集PBSC,在动员和采集过程中给予相应的身心护理。结果:55例供者均顺利完成PBSC动员和采集,不良反应较少而且可预见、可控制,所有供者采集物单个核细胞数(MNC)和CD+34细胞数均达到移植要求。结论:良好的身心护理、充分的技术准备、娴熟的操作技巧以及严密的术中监测,在最大限度减轻供者躯体不适,消除其心理疑虑的同时,保障了PBSC动员和采集顺利完成。
Objective: To explore the impact of mobilization and collection of peripheral blood stem cell(PBSC) on unrelated donors and related nursing measures.Methods: Subcutaneous injection of recombinant human granulocyte colony-stimulating factor(rhG-CSF) was given to the 55 unrelated donors for 3-5 days and CS-3000 plus model blood cell separator was used to collect PBSC.Corresponding physical and psychological nursing care was applied to the donors in the mobilization and acquisition process.Results: PBSC mobilization and collection were successfully completed in 55 unrelated donors.Adverse reactions were less and they could be predictable and controlled.The collected mononuclear cells(MNC) and CD+34 plus cell count reached the transplant request.Conclusion: The good physical and mental care,adequate technical preparation,skilled techniques as well as close intraoperative monitoring can ensure the successful completion of mobilization and collection of PBSC on the basis of eliminating donor's psychological concerns and discomfort in the body.
出处
《齐鲁护理杂志》
2009年第2S期7-8,共2页
Journal of Qilu Nursing
关键词
造血干细胞
动员
采集
无关供者
护理
Hematopoietic stem cell
Mobilization
Collection
Unrelated donor
Nursing
