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HEREDITARY PROTEIN S DEFICIENCY——SURVEY OF A CHINESE FAMILY

HEREDITARY PROTEIN S DEFICIENCY——SURVEY OF A CHINESE FAMILY
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摘要 A 76-year-old woman was diagnosed as having left lilac deep vein thrombosis due to a hereditary deficiency of protein S, seventeen members of her family were studied with the measurements of total protein S (TPS), free protein S (FPS), protein C (PC) and anti-thrombin-Ⅲ(AT-Ⅲ). The results showed that the level of FPS of thepatient was only 7%, while that of TPS 137.1%. Her secondson had a low FPS level (13.4%) too, and his TPS level was 48.1%. PC and AT-Ⅲwere all normal It was thus the first case of hereditary PS dificiency reported in China. A 76-year-old woman was diagnosed as having left lilac deep vein thrombosis due to a hereditary deficiency of protein S, seventeen members of her family were studied with the measurements of total protein S (TPS), free protein S (FPS), protein C (PC) and anti-thrombin-Ⅲ (AT-Ⅲ). The results showed that the level of FPS of thepatient was only 7%, while that of TPS 137.1%. Her secondson had a low FPS level (13.4%) too, and his TPS level was 48.1%. PC and AT-Ⅲ were all normal It was thus the first case of hereditary PS dificiency reported in China.
出处 《Medical Bulletin of Shanghai Jiaotong University》 CAS 1989年第Z1期51-54,共4页 上海交通大学学报(医学英文版)
关键词 PROTEIN S free PROTEIN S PROTEIN C protein S free protein S protein C
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参考文献3

  • 1瞿嘉珉,邵慧珍,徐也鲁,王振义.纯化一种新的人维生素K依赖性蛋白质——蛋白S[J]上海第二医科大学学报,1987(02).
  • 2顾敏祥,邵慧珍,徐也鲁,王振义.人血浆蛋白C的纯化及其抗血清制备[J]上海第二医科大学学报,1987(02).
  • 3王瑞年,张惠珠,丁怀翌,林淑英,过鑫昌,陈赛娟.原发性抗凝血酶Ⅲ缺乏症一例报告[J]上海第二医学院学报,1984(04).

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