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晚期胃肠道恶性肿瘤56例临床治疗体会

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摘要 目的:观察FOLFOX4方案治疗晚期胃肠道恶性肿瘤临床疗效及其毒副作用。方法:56例晚期胃肠道恶性肿瘤患者采用FOLFOX4方案化疗,每2 w为1个周期,治疗4~6个周期后评价疗效及毒副反应。结果:56例均可评价疗效,结直肠癌37例,CR1例、PR12例,有效率35.14%;胃癌19例,CR 1例、PR 9例,有效率52.63%;总有效率为41.07%。毒副反应主要为胃肠道反应、末鞘神经毒性、骨髓抑制及静脉炎等,未见因毒副反应而终止治疗者,无治疗相关性死亡。结论:FOLFOX4方案治疗晚期胃肠道恶性肿瘤耐受性较好,疗效较满意。
作者 马月琴
出处 《临床医药实践》 2010年第5X期566-567,共2页 Proceeding of Clinical Medicine
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