摘要
对14例≤59岁与44例≥60岁的消化性溃疡或胃炎并发上消化道出血患者,测急性出血期及大便转黄后3天内的血清超氧化物歧化酶(SOD)。结果表明≥60岁组在急性出血期的血清SOD明显高于≤59岁与正常对照组,血红蛋白明显低于而大便转黄时间明显长于≤59岁组;二组在大便转黄后的SOD均明显高于急性出血期及正常对照组。认为≥60岁组因血红蛋白明显减低及止血时间明显延长,因此组织缺氧较重、持续时间较长,刺激组织有较多SOD 产生和(或)释放。用SOD与别嘌呤醇对预防和治疗消化性溃疡出血可能有助。
SOD in 58 cases with acute hem-orrhage of upper digestive tract co-mbined with peptic ulcer or gastritiswas determined.SOD in the group 1(≥60 years,44 cases)during acutehemorrhage was much higher than inthe group 2(<60 years,14 cases)and in the normal group(150 cases).SOD in groups 1 and 2 after ceasinghemorrhage was much more higherthan in normal group and than duringhemorrhage.Hemoglobin in the group 1 wasmuch lower than in the group 2 andthe time of ceasing hemorrhage wasmuch longer than in the group 2,so that SOD in group 1 was moreproduced and/or discharged due tolong and serious anoxia of the tissuesSOD is probably helpful in prev-ention and treatment of hemorrhagewith peptic ulcer.
