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脑梗死患者治疗前后血浆生长抑素和P物质含量的变化及临床意义 被引量:5

The changes of somatostation and substance P levels and their clinical significance in patients with cerebral infarction
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摘要 目的 探讨脑梗死患者治疗前后血浆生长抑素 (SS)和 P物质 (SP)含量的变化。方法 应用放射免疫分析法对 33例脑梗死患者进行了治疗前后血浆 SS、SP含量测定 ,并以 35名正常健康人作对照。结果 脑梗死患者在治疗前血浆 SS水平高于正常人组 (P<0 .0 1) ,治疗后 2周则与正常人组差异无显著性 (P>0 .0 5 ) ,SP在治疗前则显著地低于正常人组 (P<0 .0 1) ,治疗后 2周 SP水平有所升高 ,但与正常人比较差异有显著性 (P<0 .0 5 )。结论 血浆 SS、SP水平与脑梗死有关 。 Objective To explore the changes of plasma somatostation and substance p levels before and after treatment in patients with cerebral infarction.Methods The levels of plasma somatostation and substance p were detected by RIA in 33 cases before and after in cerbral infarction and 35 cases in normal controls.Results Before treatment the level of somatostation was higher than that in normal controls( P <0.01).Two weeks after treatment no significance( P >0.05).Before treatment the substance p level was lower than that in normal controls( P <0.01).Two weeks after treatment the level of substance P raised but till lower than that in the normal controls( P <0.05).Conclusion somatostation and substance p might play a role in the onset and development of cerebral infarction.
出处 《淮海医药》 2002年第6期485-486,共2页 Journal of Huaihai Medicine
关键词 脑梗塞 生长抑素 P物质 放射免疫分析法 Cerebral infarction Somatostation Substance P
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