摘要
用光镜和电镜观察了13例烟雾病人中的12例颞浅A和6例脑膜中A,其主要病变是:内膜平滑肌细胞增生,内膜增厚,中膜和内膜肌细胞破坏,浓缩的细胞器散在于肌细胞间和内弹力板内外侧间质,内弹力板断裂。这些变化与烟雾病颈内动脉末端的病变相同,与炎性血管病、动脉粥样硬化不同,是烟雾病固有的病变。烟雾病不仅是脑血管病,颈外A系统亦可受累。
12 superficial temporal arteries (STA) and 6 middle meningeal arteries (MMA)of 12 cases of Moyamoya diseases were observed by light and electron microscopy. The main pathologic changes were: Proliferation of smoothmuscle cells (SMCs) and thickening of intima, degeneration and destruction of SMCs in media and intima, condensed organelles from destructed SMCs dispersed throughout the interstitium among the SMCs and outside and inside the elastica interna, and fragmentation of elastica interna.It was same as the changes of internal carotid A and middle cerebral A of Moyamoya disease, we had reported before. These pathologic changes were different from those of inflammatory angiopathy and of arteriosclerosis. They were characteristie for Moyamoya disease. The pathologic changes in STA and MMA. demonstrated. That Moyamoya disease invades not only ICA, but also intra and extracranial branches belong to externalcarotid artery.
出处
《中华神经外科杂志》
CSCD
北大核心
1989年第4期25-28,76+87,共6页
Chinese Journal of Neurosurgery
