摘要
目的 对 6例系统性红斑狼疮 (SLE)终末期肾病患者的肾移植情况进行总结。方法 对 6例终末期狼疮肾病肾移植患者的临床、实验室资料和手术后随访情况进行分析。结果 6例患者均为女性 ,平均病程 4 4年 ,进行移植手术时全身病情稳定 ;术前均使用激素和 /或免疫抑制剂控制SLE病情 ,手术后免疫抑制剂使用情况差异无显著性 ,术后平均随诊时间为 2 4 2个月 ,无 1例发生急、慢性排异反应及狼疮肾病复发 ,移植肾功能良好。结论 终末期狼疮肾病患者的移植肾存活及功能状况良好 ,无狼疮肾病复发 。
Objective To summarize the clinical and laboratory data of 6 renal transplantation patients with end stage renal disease caused by lupus nephritis.Methods Clinical and laboratory data as well as the follow up data of 6 renal transplantation patients with end stage renal disease caused by lupus nephritis were collected and analyzed.Results The average course of these 6 patients was 4 4 years.All patients′systemic disorders were generally stable at the time of transplantation.Prednisone and/or immune suppressive agents were used to control systemic disorders.Neither acute nor chronic rejection reaction was observed among these patients.The drugs used for rejection control were similar.All renal allografts were in good condition and no lupus nephritis recurrence was observed.Conclusion All renal allografts were in good condition among patients with end stage renal disease caused by lupus nephritis.Renal transplantation is an effective way to treat end stage lupus nephritis.
出处
《中华风湿病学杂志》
CAS
CSCD
2002年第5期357-359,共3页
Chinese Journal of Rheumatology
关键词
狼疮肾病
终末期
患者
肾移植
临床分析
Lupus nephritis
Renal transplantation
Treatment outcome
