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乌体林斯联合拉米夫定对慢性乙型肝炎的疗效 被引量:1

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摘要 目的 增强机体的免疫功能,提高对慢性乙肝的疗效。方法 每日肌肉注射乌体林斯,同时口服拉米夫定,每2周测ALT,每月测HBsAg、HBeAg、抗HBs、抗HBc及HBV-DNA。结果 在检测肝功能指标(ALT、TBIL)及乙型肝炎病毒标志(HBeAG、HBV-DNA)的项目中,治疗组与对照组差异均有显著意义(P<0.05)。结论两药合用治疗慢性乙肝是安全有效的疗法。
出处 《中国生物制品学杂志》 CAS CSCD 2002年第5期306-306,309,共2页 Chinese Journal of Biologicals
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  • 1Lee W.Hepatitis B Virus Infection[J].N Engl J Med,1997,337:1733.
  • 2Hoofnagle JH,DiBisceglie AM.The treatrnent of chrnic viral hepatitis[J].N Engl J Med.1997,336:347.
  • 3Lai CL,Chien RN,Leung NWY,et al.A one -year trial of lamivudine for chronic hepatitis B[J].N Engl J Med,1998,339:61.
  • 4Sokal E,Roberta EA,Mieli-Vergani G,et al.Dose—finding and safety of Iamivudine in children and adolescents with ehronie hepatitis B(abstract)[J].Hepatology,1998,28(4pt2)489A.
  • 5Lai CI,Ching CK,Tung AKM,et a1.Lamivudine is effective in suppreasing bepatitis B virus DNA in chinese hepatitis B surface antigen carriers:a placebo-controlled trial[J].Hepatology,1997,25:241.
  • 6Allen MI,Dealauriers M,Andrews W,et a1.Identification and characterization of mutations in hepatitis B virus resistant to almivudine[J].Hepatology ,1998,27:1670.
  • 7Chayama K,Yoshiyuki S,Kobayashi M,et al,Emergence and takeover of YMDD matif matant hepatitis B virus duing long-term lamivudine therapy and re-takeover by wild type after cessation of therapy[J].Hepatology,1998.27:1711.
  • 8Niesters HGM,Honkoop P,Haagama EB,et a1.Identification of more than one mutation in the hepatitis B virus polymerase gene arising during prolonged lamivudine treatment [J].J Infect Dis,1998,177:1382.
  • 9Tipplea GA,Ma MM,Fischer KP,et al.Mutation in HBV RNA-dependent DNA polymerase confers resistance to lamivadine in vivo[J].Hepatology,1996.24:714.
  • 10Melegari M, Scaglioni PP, Wands JR,et al.Hepstitis B virus mutations associated with 3TC and Famciclovir administration are replication delective[J]. Hepatology, 1998,27:628.

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