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替吉奥联合姑息性疗法治疗老年晚期结肠癌的临床效果分析 被引量:4

Clinical analysis of the tffect on Tijiaao combined with palliative treatment of elderly patients with advanced colon cancer
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摘要 目的:观察替吉奥联合姑息性疗法治疗老年晚期结肠癌的临床效果,总结临床意义。方法:收治晚期结肠癌患者52例,随机分两组,各26例,对照组使用替吉奥单药治疗方法,观察组在对照组基础上加行姑息性治疗的方法,观察治疗之后的症状改善程度、疾病控制率和不良反应。结果:观察组患者的治疗总有效率明显优于对照组(P<0.05);治疗后患者的临床症状均得到了很好的改善(P<0.05)。结论:对于老年晚期结肠癌患者,替吉奥联合姑息性疗法的治疗效果显著,能有效改善患者病情,提高患者的生活质量。 Objective:To observe the clinical effect of Tijiaao combined with palliative treatment of elderly patients with advancedcolon cancer,to sum up the clinical significance.Methods:52 patients with advanced colon cancer were selected,they wererandomly divided into two groups,26 cases in each,the control group using Tijiaao monotherapy treatment method, the observationgroup based on the control group with additional palliative treatment method.To observe the improvement of symptoms,diseasecontrol rate and adverse reactions after treatment.Results:The total effective rate of the observation group was significantly betterthan that of the control group(P<0.05),the clinical symptoms of the patients were improved significantly(P<0.05).Conclusion:Forelderly patients with advanced colon cancer patients,Tijiaao combined with palliative treatment effect is significantly,caneffectively improve the patient's condition,improve the quality of life of the patients.
作者 顾晓华 冒志明 Gu Xiaohua;Mao Zhiming(Department of General Surgery,Boai Hospital of Rugao City 226500)
出处 《中国社区医师》 2015年第34期142-142,144,共2页 Chinese Community Doctors
关键词 替吉奥单药治疗 姑息性治疗 晚期结肠癌 老年 Tijiaao monotherapy Palliative treatment Advanced colorectal cancer Elderly
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  • 1Gallagher DJ, Kemeny N. Metastatic colorectal cancer: from improved survival to potential cure. Oneology, 2010,78(3-4): 237-248.
  • 2Davies JM, Goldberg RM. Treatment of metastatic colorectal cancer. Semin Oncol, 2011,38(4) : 552-560.
  • 3Imamura H, Furukawa H, Kishimoto T, et al. Phase Ⅱ study of 2-week TS-1 administration followed by 1-week rest forgastric cancer. Hepatogastroenterology, 2007,54 (79) : 2167- 2171.
  • 4Sakuramoto S, Sasako M, Ymaguchi T, et al. Adjuvant chemotherapy for gastric cancer with S-l, an oral fluropyrimi- dine. N Engl J Med, 2007,357(18) : 1810-1820.
  • 5Koizumi W, Narahara H, Hara T et al. S-1 plus cisplatin ver- sus S-1 alone for first-line treatment of advanced gastric can- cer (SPIRITS trial): a phase m trial. Lancet Oncol, 2008,9 (3): 215-221.
  • 6Yoshikawa T, Omura K, Kobayashi O,et al. A phase II study of preoperative chemotherapy with S-1 plus cisplatin followed by D2/D3 gastrectomy for clinically serosa-positive gastric can- cer. Eur J Surg Oncol, 2010,36(6): 546-551.
  • 7Lee DJ, Lee J, Lee HY,et al. Salvage S-1 monotherapy in metastatic colorectal cancer patients who failed irinotecan- based or oxaliplatin-based chemotherapy. Med Oncol, 2011, 28(Suppl 1) : $291-$294.

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