摘要
目的:分析氨氯地平联合阿托伐他汀钙片在高血压合并冠心病患者治疗中的临床应用效果及安全性。方法:收治高血压合并冠心病患者80例,平分为两组,对照组行氨氯地平治疗,试验组在此基础上加阿托伐他汀钙片治疗。观察两组患者用药前后血脂、血压变化情况,以及监测患者的不良反应。结果:两组患者的血压(舒张压、收缩压)和血脂(HDL-C、TG、TC)水平在治疗后都有所下降,两组数据差异具有统计学意义,P<0.05。试验组出现恶心、头晕1例,对照组出现心慌2例,经用药调整均有所缓解。结论:高血压合并冠心病患者行氨氯地平联合阿托伐他汀钙片治疗能够有效改善患者的血压和血脂水平,患者的临床不良反应较少。
Objective:To analyze the clinical effect and safety of amlodipine combined with atorvastatin calcium tablets in thetreatment of patients with hypertension and coronary heart disease.Methods:80 patients with hypertension combined with coronaryheart disease were selected.They were divided into the two groups.Patients in the control group were treated with amlodipine.Patients in the experimental group treated with atorvastatin calcium tablets on the basis of the control group.The blood lipid andblood pressure were observed before and after treatment in the two groups,and the adverse reactions were observed.Results:Theblood pressure(diastolic blood pressure, systolic blood pressure)and blood lipids(HDL-C,TG,TC)levels in the two groups weredecreased after treatment,and the difference between groups was statistically significant,P<0.05.In the experimental group,1 casewas with nausea and dizziness,while in the control group 2 cases were with palpitation phenomenon.All patients were relieved bymedication adjustment.Conclusion:Amlodipine combined with atorvastatin calcium tablets in the treatment of patients withhypertension and coronary heart disease can effectively improve the patients' blood pressure and blood lipid level,and the clinicaladverse reactions are less.
作者
孙予州
Sun Yuzhou(Affiliated Hospital of Jiyuan Health School,Henan Province 459000)
出处
《中国社区医师》
2016年第14期40-40,42,共2页
Chinese Community Doctors
关键词
氨氯地平
阿托伐汀钙片
高血压
冠心病
Amlodipine
Atorvastatin calcium tablets
Hypertension
Coronary heart disease
