摘要
目的:观察慢性阻塞性肺疾病(COPD)患者急性加重期甲状腺激素水平的动态变化。方法:将65例COPD急性加重期患者作为观察组,65例健康人为对照组。观察组在入院次日及出院前1d、对照组分别测定血清甲状腺激素总三碘甲状腺原氨酸(TT_3)、血清总甲状腺素(TT_4)、血清游离三碘甲状腺原氨酸(FT_3)、血清游离甲状腺素(FT_4)及促甲状腺生成素(TSH)水平,观察急性发作期和缓解期COPD患者及健康对照组血清甲状腺素水平,了解甲状腺功能的动态变化。结果:观察组血清TT_3、FT_3、TSH水平明显低于对照组(P<0.05);治疗后,观察组血清TT_3、FT_3水平均有不同程度的提升(P<0.05)。结论:血清甲状腺激素水平的动态变化反映了COPD患者急性加重期病情的严重程度,有助于评估疾病预后。
Objective:To observe the dynamic changes of thyroid hormone levels of patients with chronic obstructive pulmonarydisease in acute exacerbation.Methods:65 patients with chronic obstructive pulmonary disease in acute exacerbation were as theobservation group.65 healthy person were as the control group.The serum thyroid hormone total triiodothyronine(TT3),serum totalthyroid hormone(TT4),serum free triiodothyronine(FT3),serum free thyroid hormone(FT4) and thyroid stimulating hormone(TSH)levels were respectively determinated in the observation group on second day after admission and 1 day before discharge and thecontrol group.The serum thyroid hormone levels of patients with chronic obstructive pulmonary disease in acute phase andremission and healthy control group were observed.The dynamic changes of thyroid function were understanded.Results:Theserum TT3,FT3 and TSH levels of the observation group were significantly lower than those of the control group(P<0.05).Aftertreatment,the serum TT3 and FT3 levels of the observation group were significantly improved(P<0.05).Conclusion:The dynamicchanges of serum thyroid hormone levels reflect the illness severity of patients with chronic obstructive pulmonary disease inacute exacerbation,which can help to evaluate the prognosis of the disease.
作者
张辉
Zhang Hui(Department of Internal Medicine,Yankuang Group General Hospital Ji Three Branch Hospital 273500)
出处
《中国社区医师》
2016年第6期153-153,155,共2页
Chinese Community Doctors
关键词
慢性阻塞性肺疾病
急性加重期
甲状腺激素水平
动态变化
Chronic obstructive pulmonary disease
Acute exacerbation
Thyroid hormone levels
Dynamic changes
