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糖皮质激素联合特布他林治疗慢性阻塞性肺疾病急性加重期的疗效观察 被引量:3

Observation on the therapeutic effect of glucocorticoid combined with terbutaline in the treatment of acute exacerbation of chronic obstructive pulmonary disease
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摘要 目的:探讨慢性阻塞性肺疾病急性加重期(AECOPD)采用药物联合治疗的疗效。方法:收治AECOPD患者96例,随机分为对照组(特布他林)和试验组(特布他林+糖皮质激素)。结果:试验组临床有效率显著高于对照组(P<0.05);治疗后试验组Pa CO2、Pa O2均显著改善,且显著优于对照组(P<0.05),且不良反应显著少于对照组(P<0.05)。结论:糖皮质激素联合特布他林治疗AECOPD可取得显著的疗效,安全性相对较高。 Objective:To investigate the therapeutic effect of combined drug therapy in acute exacerbation of chronic obstructive pulmonary disease.Methods:96 cases of AECOPD were selected.They were randomly divided into the control group(terbutaline)and the experimental group(terbutaline combined with glucocorticoid hormone).Results:The clinical effective rate of the experimental group was significantly higher than the control group(P<0.05);After the treatment,both the PaCO2 and PaO2 in the experimental group were significantly improved,and significantly better than the control group(P<0.05),in addation,the adverse reaction was significantly lower than the control group(P<0.05).Conclusion:Glucocorticoid combined with terbutaline in the treatment of AECOPD has significant therapeutic effect,and it also has relative high safety.
作者 陈梓实 Chen Zishi(Department of Internal Medicine,the Center Hospital of Lankou Town,Dongyuan County of Heyuan City,Guangdong Province 517564)
出处 《中国社区医师》 2016年第32期21-22,共2页 Chinese Community Doctors
关键词 特布他林 糖皮质激素 慢性阻塞性肺疾病急性加重期 Terbutaline Glucocorticoid hormone Acute exacerbation of chronic obstructive pulmonary disease
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