摘要
目的:探讨针灸结合阿仑膦酸钠治疗绝经后骨质疏松症的疗效。方法:40例绝经后骨质疏松症患者随机分为治疗组和对照组各20例,均给予钙剂(钙尔奇600 mg/d)、骨化三醇(罗盖全)0.25 ug/d及阿仑膦酸钠(福善美)70 mg/周口服,治疗组选用百会、大椎、脾俞、肾俞、命门、神阙、足三里、三阴交等穴,采用针刺和艾灸相结合的方法。两组均连续治疗6个月后,观察和比较患者临床症状积分和骨代谢的变化。结果:治疗6个月后两组血钙、血磷与治疗前比较均差异无统计学意义;两组Ⅰ型胶原羧基末端肽(β-Crosslaps)均较治疗前降低,腰椎和股骨颈骨密度及血清骨钙素(OPG)均较治疗前上升,治疗组改善更明显,与对照组比较差异有统计学意义(P<0.05)。两组患者症状积分均得到改善,治疗组较对照组下降更为明显(P<0.01)。结论:针灸结合阿仑膦酸钠能有效增加绝经后骨质疏松患者腰椎、股骨颈骨密度,改善患者症状积分,有较好的治疗效果。
Objective To explore the clinical efficacy of Acupuncture and Alendronate in the treatment of Postlnenopausal osteoporosis.Method 40 cases of postlnenopausal osteoporosis were randomly divided into treatment group 20 cases and control group20 cases. Alendronate sodium was taken by two groups simultaneously. The two group were treated with a table of Caltrate D 600 mgand calcitriol per day. The treatment group was treated by Acupuncture and moxibustion at Baihui, Dazhui, Pishu, Shenshu, Mingmen,Shenque,Zusanli,Sanyinjiao respectively. Six months later,the integral of clinical symptoms and bone metabolism were detected.Results After 6 months treatment, the lumbar spine and femoral neck BMD, serum osteoprotegerin of two groups increased thanbefore,The treatment group was higher than that of control group(P <0. 05). p - Crosslaps of two groups were delined in treatmentgroup ( P < 0. 05 ). The treatment group was lower than that of control group ( P < 0. 05 ). There was no significant difference betweentwo groups in blood calcium and phosphorus(P >0. 05). Clinical symptoms were improved significantly in the treatment group (P <0. 01). Conclusion The combination of Acupuncture with Alendronate is a good method to the patients of Postlnenopausal osteoporosis.
作者
林红晓
王东岩
LIN Hong - xiao;WANG Dong - yan(Osteoporosis Department, The First People's Hospital of Lianyungang ,Lianyungang 222000,China)
出处
《吉林医学》
CAS
2016年第7期1614-1615,共2页
Jilin Medical Journal
