摘要
目的:比较、分析两种测定方法检测血清抗甲状腺抗体在临床诊断中的应用价值。方法:收治甲状腺疾病患者120例作为观察组,同期选择体检的正常人员100例作为对照组,均采用自动化学发光免疫分析法(CLIA)以及放射免疫分析法(RIA)测定血清抗甲状腺抗体,比较不同方法的检测结果。结果:在抗甲状腺球蛋白抗体(抗Tg Ab)以及抗甲状腺过氧化物酶抗体(抗TPOAb)检测结果方面,CLIA法与RIA法差异不具有统计学意义(P>0.05)。结论:对于血清抗甲状腺抗体的测定,采用CLIA法与RIA法都能取得较好的检测结果,可根据医院的实际情况合理选择,必要时联合使用。
Objective:To compare the clinical diagnostic value of two different assay methods in detecting serum anti thyroid antibodies.Methods:120 cases with thyroid disease were selected as the observation group,at the same time,100 healthy people with examination were selected as the control group.All patients were tested for serum anti-thyroid antibodies using automated chemiluminescent immunoassay(CLIA)and radioimmunoassay(RIA).We compared the detection results of the different methods.Results:There was little difference between the results of CLIA and RIA in the detection of anti-thyroglobulin antibody(anti-TgAb)and anti-thyroid peroxidase antibody(anti-TPOAb)test results,and the difference was not statistically significant(P>0.05).Conclusion:For the determination of serum anti-thyroid antibodies,using CLIA and RIA method can achieve better detection results,according to the actual situation of the hospital to choose a reasonable detection method,if necessary,make a combination use of the two methods.
作者
张增荣
Zhang Zengrong(Department of Clinical Laboratory,Infectious Disease Hospital of Jining City,Shandong Province 272031)
出处
《中国社区医师》
2017年第2期115-116,共2页
Chinese Community Doctors
