摘要
目的研究糖皮质激素治疗急性重度淤胆性肝病的临床效果。方法选取98例急性重度淤胆性肝病患者,随机分为两组,每组49例。观察组采用糖皮质激素治疗,对照组采用熊去氧胆酸治疗。连续治疗2周,对两组急性重度淤胆性肝病患者的治疗效果及总胆红素变化情况进行对比分析。结果经过治疗,观察组的总有效率为93.88%,对照组的总有效率为63.27%,观察组治疗效果优于观察组,差异具有统计学意义(P<0.05)。结论糖皮质激素治疗急性重度淤胆性肝病的临床效果显著,值得在临床实践中应用推广。
Objective To study the clinical effect of glucocorticoid in the treatment of acute severe cholestasis liver disease.Methods98casesof acute severe cholestasis liver disease admitted were randomly divided into two groups,49cases in each group.The observation group with glucocorticoidtreatment,the control group using ursodeoxycholic acid treatment.The treatment effect and the change of total bilirubin of two groups ofpatients with acute severe cholestasis liver disease were compared and analyzed in2weeks.Results After treatment,the total effective rate of observationgroup was93.88%,the total effective rate of control group was63.27%,the observation group was better than the observation group,statisticallysignificant(P<0.05).Conclusion Glucocorticoid in the treatment of acute severe cholestasis liver disease has significant clinical effect,it isworthy to be popularized in clinical practice.
作者
唐浩伦
Tang Hao-lun(Fourth People 's Hospital of Panzhihua City,Panzhihua,Sichaun,617000,China)
出处
《当代医学》
2017年第6期95-96,共2页
Contemporary Medicine
关键词
糖皮质激素
急性重度淤胆性肝病
治疗效果
Glucocorticoid
Acute severe cholestasis liver disease
Therapeutic effect
