摘要
目的探讨宫颈锥形切除术与根治性宫颈切除术治疗早期宫颈癌的临床效果。方法 86例早期宫颈癌患者,根据手术方式的不同随机分为研究组和对照组,各43例。研究组采用根治性宫颈切除术;对照组采用宫颈锥形切除术治疗。记录两组患者住院一般情况(手术时间、术中出血量、排气时间及住院时间),并比较两组患者临床疗效。结果研究组手术时间为(147.2±15.1)min、术中出血量为(228.5±11.9)ml、排气时间为(22.8±9.1)h及住院时间为(11.5±3.2)d,均显著低于对照组的(171.5±18.9)min、(273.4±12.1)ml、(38.1±11.2)h及(17.6±4.3)d,差异具有统计学意义(P<0.05)。经手术治疗后随访3年,研究组患者中疗效优秀30例、良好11例,临床疗效优良率为95.35%;对照组分别为31例、9例及93.02%,两组优良率比较差异无统计学意义(P>0.05)。结论根治性宫颈切除术应用于早期宫颈癌临床治疗中,疗效与宫颈锥形切除术相近,但术中、术后临床表现更佳,手术安全性更高,更适应于有生育要求的年轻患者,值得临床推广应用。
Objective To explore the clinical effect of cervical conization and radical trachelectomy in the treatment of early stage cervical cancer. Methods A total of 86 early stage cervical cancer patients were divided by different surgical methods into research group and control group, with 43 cases in each group. The research group received radical trachelectomy, and the control group received cervical conization for treatment. Recorded the general hospitalized situation (operation time, intraoperative blood loss, exhaust time and hospitalization time) and compared the clinical effect in two groups. Results The research group had operation time as (147.2±15.1) min,intraoperative blood loss as (228.5±11.9) ml, exhaust time as (22.8±9.1) h and hospitalization time as (11.5±3.2) d,which were all lower than (171.5±18.9) min, (273.4±12.1) ml, (38.1±11.2) h and (17.6±4.3) d in the controlgroup. Their differences had statistical significance (P<0.05). Follow-up for 3 years after surgery showed thatthe research group had 30 excellent cases, 11 good cases, with excellent-good rate in clinical effect as 95.35%,which were 31 cases, 9 cases and 93.02% in the control group. There were no statistically significant difference of excellent-good rate between two groups (P>0.05). Conclusion Radical trachelectomy applied in clinical treatment of early stage cervical cancer, shows similar curative effect to cervical conization, while with better intraoperative and postoperative clinical manifestation, higher operation safety, and it is more suitable for young patients with fertility requirements. So it is worthy of clinical popularization and application.
作者
郭芳
GUO Fang(Department of Obstetrics, Guangdong Huizhou Boluo People’s Hospital,Huizhou 516100, China)
出处
《中国现代药物应用》
2017年第3期22-24,共3页
Chinese Journal of Modern Drug Application
