摘要
目的探讨卡前列素氨丁三醇联合纱条宫腔填塞治疗凶险性前置胎盘的临床效果。方法 72例凶险性前置胎盘患者,按照治疗方式不同分为实验组和常规组,各36例。实验组采取卡前列素氨丁三醇联合纱条宫腔填塞处理,常规组采取催产素注射联合纱条宫腔填塞处理,对比两组患者治疗效果。结果两组患者术中出血量比较差异无统计学意义(P>0.05);术后2 h及术后24 h实验组患者阴道出血量分别为(31.05±15.76)、(14.57±11.36)ml,显著少于常规组的(61.25±21.09)、(29.15±12.37)ml,差异有统计学意义(P<0.05)。实验组患者在治疗期间出现恶心症状8例(22.22%),呕吐反应4例(11.11%),胸闷症状2例(5.56%),不良反应发生率为38.89%;常规组患者治疗期间出现恶心症状3例(8.33%),胸闷症状1例(2.78%),无呕吐患者,不良反应发生率为11.11%;实验组患者不良反应发生率明显高于常规组,差异有统计学意义(P<0.05)。结论治疗凶险性前置胎盘采取卡前列素氨丁三醇联合纱条宫腔填塞方式,经由生理治疗与物理控制多方面处理,可及时止血,降低大出血风险,效果显著,值得推广应用。
Objective To explore the clinical effect of carboprost tromethamine combined with gauze intrauterine tamponade in the treatment of dangerous placenta previa. Methods A total of 72 dangerous placenta previa patients were divided by different treatment methods into experimental group and conventional group,with 36 cases in each group. The experimental group received carboprost tromethamine combined with gauze intrauterine tamponade, and the conventional group received oxytocin injections combined with gauze intrauterine tamponade. Treatment effect was compared in two groups. Results There was no statistically significant difference in intraoperative bleeding volume in two groups (P>0.05). The experimental group had vaginal bleeding volume in postoperative 2 and 24 h respectively as (31.05±15.76) and (14.57±11.36) ml, which were obviouslyless than (61.25±21.09) and (29.15±12.37) ml in the conventional group. Their differences had statistical significance (P<0.05). The experimental group had 8 nausea symptom cases (22.22%), 4 vomiting reaction cases(11.11%), 2 symptom of chest tightness cases (5.56%), with incidence of adverse reaction rate as 38.89% duringtreatment. The conventional group had 3 nausea symptom cases (8.33%), 1 symptom of chest tightness case (2.78%), 0vomiting case, with incidence of adverse reactions as 11.11%. The experimental group had obviously higher incidence of adverse reactions than the conventional group, and the difference had statistical significance (P<0.05). Conclusion Combination of carboprost tromethamine and gauze intrauterine tamponade in the treatment of dangerous placenta previa, through physical therapy and physical control of various processing, can timely stop bleeding, reduce the risk of massive haemorrhage with remarkable effect, and it is worthy of popularization and application.
作者
唐敏
TANG Min(Hunan Yongzhou City Maternal and Child Care Service Center,Yongzhou 425000, China)
出处
《中国现代药物应用》
2017年第3期109-111,共3页
Chinese Journal of Modern Drug Application
关键词
卡前列素氨丁三醇
纱条宫腔填塞
凶险性前置胎盘
疗效
Carboprost tromethamine
Gauze intrauterine tamponade
Dangerous placenta previa
Curative effect
