摘要
目的评价双柏散外敷治疗肝癌轻度癌痛的临床疗效。方法 36例肝癌轻度癌痛患者,按照随机的分配原则分成对照组(19例)与观察组(17例)。对照组患者给予塞来昔布胶囊治疗,观察组患者应用双柏散外敷治疗。比较两组治疗后的临床疗效和不良反应发生情况。结果治疗后,观察组患者疼痛缓解率为88.2%,明显高于对照组的68.4%,差异有统计学意义(P<0.05)。治疗前,观察组与对照组的疼痛评分分别为(2.76±0.65)分与(2.81±0.32)分,治疗后,观察组的疼痛评分为(1.02±0.27)分,对照组的疼痛评分为(2.54±0.47)分。治疗前两组疼痛评分比较差异无统计学意义(P>0.05);治疗后观察组患者的疼痛评分优于对照组,差异有统计学意义(P<0.05)。观察组不良反应发生率5.9%明显低于对照组26.3%,差异有统计学意义(P<0.05)。结论双柏散外敷治疗肝癌轻度癌痛的临床疗效好,临床应用简单方便,不良反应发生率低,可在临床中推广应用。
Objective To evaluate clinical effect by external application of Shuangbai powder in the treatment of mild liver cancer pain. Methods A total of 36 patients with mild liver cancer pain were randomly divided into control group (19 cases) and observation group (17 cases). The control group received celecoxib capsules for treatment, and the observation group received external application of Shuangbai powder for treatment.Comparison was made on clinical effect and adverse reactions between the two groups. Results After treatment,the observation group had obviously higher pain remission rate as 88.2% than 68.4% in the control group, and the difference had statistical significance (P<0.05). Before treatment, the observation group and the control group respectively had pain score as (2.76±0.65) points and (2.81±0.32) points. After treatment, the observation grouphad pain score as (1.02±0.27) points, and the control group had pain score as (2.54±0.47) points. There was no statistically significant difference in pain score before treatment between two groups (P>0.05). The observation group had better pain score after treatment than the control group, and the difference had statistical significance (P<0.05). The observation group had obviously lower incidence of adverse reactions as 5.9% than 26.3% in the controlgroup, and the difference had statistical significance (P<0.05). Conclusion External application of Shuangbai powder provides excellent clinical effect in the treatment of mild liver cancer pain. This method shows easy and convenient clinical application, and low incidence of adverse reactions. It is worth clinical promotion and application.
作者
刘峥峥
LIU Zheng-zheng(Department of Medical Oncology, Zhongshan City Hospital of Traditional Chinese Medicine, Zhongshan 528400, China)
出处
《中国现代药物应用》
2017年第3期177-179,共3页
Chinese Journal of Modern Drug Application
关键词
双柏散
外敷
肝癌
轻度癌痛
Shuangbai powder
External application
Liver cancer
Mild cancer pain
