摘要
目的研究分析氨酚曲马多对带状疱疹及带状疱疹后遗神经痛患者的治疗效果和安全性。方法 74例带状疱疹及带状疱疹后遗神经痛患者,随机分为治疗组及对照组,各37例。治疗组患者使用氨酚曲马多片治疗,对照组患者使用布洛芬缓释胶囊治疗。对比两组患者的临床疗效及不良反应发生情况。结果治疗组总有效率83.78%高于对照组的62.16%,差异具有统计学意义(χ~2=4.385,P<0.05)。治疗组患者不良反应发生率为13.51%,对照组患者不良反应发生率为18.92%,比较差异无统计学意义(χ~2=0.398,P>0.05)。结论带状疱疹及带状疱疹后遗神经痛患者接受氨酚曲马多治疗的效果良好,见效快,安全性高,临床中可以推广使用。
Objective To study and analyze the treatment effect and security of paracetamol and tramadol in the treatment of herpes zoster and postherpetic neuralgia.Methods A total of74patients with herpes zoster and postherpetic neuralgia were randomly divided into treatment group and control group,with37cases in each group.The treatment group received paracetamol and tramadol tablets for treatment,and the control group received ibuprofen sustained release capsules for treatment.Comparison were made on clinical curative effect and occurrence of adverse reactions in two groups.Results The treatment group had higher total effective rate as83.78%than62.16%in the control group,and the difference had statistical significance(χ2=4.385,P<0.05).The treatment group had incidence of adverse reactions as13.51%,while the control group had incidence of adverse reactions as18.92%,and the difference had no statistical significance(χ2=0.398,P>0.05).Conclusion Paracetamol and tramadol shows good effect in the treatment of patients with herpes zoster and postherpetic neuralgia with quick response and high security,and it can be promoted and applied in clinic.
作者
杨晶
尤海燕
YANG Jing;YOU Hai-yan(Heilongjiang Provincial Hospital, Harbin 150001, China)
出处
《中国现代药物应用》
2017年第6期99-100,共2页
Chinese Journal of Modern Drug Application
关键词
带状疱疹
后遗神经痛
氨酚曲马多
Herpes zoster
Postherpetic neuralgia
Paracetamol and tramadol
