期刊文献+

尼莫地平对脑出血后缺血性脑损伤的临床疗效评价 被引量:6

Clinical curative effect evaluation of nimodipine on ischemic cerebral trauma after cerebral hemorrhage
下载PDF
导出
摘要 目的:分析尼莫地平对脑出血后缺血性脑损伤的临床效果。方法:收治脑出血后缺血性脑损伤患者100例,随机分为参考组和治疗组,各50例。参考组给予常规临床治疗,治疗组在参考组的基础上加用尼莫地平治疗。对比两组患者的疗效,且观察患者治疗前后的神经功能缺损情况、日常生活能力变化及不良反应。结果:治疗组的总有效率明显高于参考组(P<0.05);治疗组治疗后NIHSS评分明显低于治疗前、参考组同期,BI评分显著更高(P<0.05)。结论:尼莫地平治疗脑出血后缺血性脑损伤患者可有效提高疗效,且有助于改善其神经功能缺损及日常生活能力。 Objective:To analyze the clinical effect of nimodipine on ischemic cerebral trauma after cerebral hemorrhage.Methods:Objective:To analyze the clinical effect of nimodipine on ischemic cerebral trauma after cerebral hemorrhage.Methods:100patients with ischemic cerebral trauma after cerebral hemorrhage were selected.They were randomly divided into thereference group and the treatment group with50cases in each.The reference group was given routine clinical treatment,and thetreatment group was given nimodipine treatment on the basis of the reference group.The curative effects of two groups werecompared.The neurological deficits before and after treatment,daily living activity changes and adverse reactions were observed.Results:The total effective rate of the treatment group was significantly higher than that of the reference group(P<0.05).TheNIHSS score after treatment in the treatment group was significantly lower than that before treatment and the reference group,andthe BI score was significantly higher(P<0.05).Conclusion:Nimodipine in the treatment of patients with ischemic cerebral traumaafter cerebral hemorrhage can effectively improve the curative effect,and help to improve the neurological deficits and daily living ability.
作者 张永 姚声涛 姚声涛 Zhang Yong;Yao Shengtao(Corresponding author);Yao Shengtao(Corresponding author)(The Affiliated Hospital of Zunyi Medical College(Guizhou Province)563003)
出处 《中国社区医师》 2017年第13期31-32,共2页 Chinese Community Doctors
关键词 脑出血 缺血性脑损伤 尼莫地平 神经功能缺损 Cerebral hemorrhage Ischemic cerebral trauma Nimodipine Neurological deficits
  • 相关文献

参考文献4

二级参考文献26

  • 1孙兴元,张艳蕉,赵宏,蒋丽艳,迟景宏,潘云志,隋欣.微创血肿碎吸引流术联合尼莫地平治疗高血压脑出血临床研究[J].神经损伤与功能重建,2006,1(2):103-104. 被引量:18
  • 2黄英,严超英.碘标记神经生长因子在缺氧新生鼠脑内的吸收[J].实用儿科临床杂志,2006,21(11):699-700. 被引量:4
  • 3Tany XQ, Cai J, Nelson KD, et al. Functional repair after dorsal root rhizotomy using nervev conduits and neurotrophic molecules [ J ]. Eur J Neurosci ,2004,20( 5 ) : 1211 - 1218.
  • 4Tuszynssssssski MH, UHS, Alksne J, et al. Growth factor gene therapy for Alzheimer dis- ease [ J ]. Neurosurg Focus, 2002,13 ( 5 ) :5.
  • 5Park IK, Lee KY, Song CW, et al. Immunohis- tochemical localization of never growth factor, glial fibrillary acidic protein and ciliary neuro- trophic factor in mesencepalon, rhombcnceph- alon, and spinal cord of" developing Mongolian gerbil [ J ]. J Vet Sci, 2002,3 ( 3 ) :239 - 245.
  • 6Lobos E, Gebhardt C, Kluge A, et al. Expres- sion of nerve growth factor (NGF) isoforms in the rat uterus during pregnancy: accumulation of precursor proNGF [ J ]. Endocrinology, 2005,146 (4) : 1922 - 1929.
  • 7Goss JR,OMalley ME,Zou L,et al. Astrocytes are the major source of nerne growth factor up- regulation following traumatic brain injury in the rat [ J ]. Exp Neurol, 1998,149 (2) : 301 - 309.
  • 8孙文,孙正芸.神经节苷脂和脑活素治疗早产儿脑室周围白质软化的疗效的观察[J].20t0,28(2):187-189.
  • 9魏丽夏,曹云涛,刘华庆,邓卫安.神经生长因子对新生鼠缺氧缺血性脑损伤后神经再生的影响[J].临床儿科杂志,2008,26(7):612-616. 被引量:12
  • 10韩富民.尼莫地平治疗高血压脑出血128例临床观察[J].中国药物与临床,2010,10(7):830-831. 被引量:17

同被引文献34

引证文献6

二级引证文献10

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部