期刊文献+

紫杉醇联合吉非替尼对食管癌患者的影响研究

Study on the effect of paclitaxel combined with gefitinib in patients with esophageal cancer
下载PDF
导出
摘要 目的:探讨紫杉醇联合吉非替尼对食管癌患者的影响。方法:收治食管癌患者62例,采取随机数字表法分为观察组与对照组各31例,对照组给予单纯放疗治疗,观察组在对照组基础上给予紫杉醇联合吉非替尼化疗治疗。结果:观察组患者治疗总有效率和患者1、3、5年生存率,治疗满意率均高于对照组(P<0.05)。结论:紫杉醇联合吉非替尼化疗可提升食管癌患者治疗有效率,延长患者生存时间。 Objective:To investigate the effect of paclitaxel combined with gefitinib in patients with esophageal cancer.Methods:62patients with esophageal cancer were selected.They were randomly divided into the observation group and the control group with31cases in each.The control group were treated with radiotherapy,and the observation group were given paclitaxel combined with gefitinib chemotherapy,based on the treatment given in the control group.Results:The total effective rate,the survival rate at1,3,5years and treatment satisfaction rate in the observation group were higher than those in the control group(P<0.05).Conclusion:Paclitaxel combined with gefitinib chemotherapy can improve the treatment efficiency and prolong the survival time of patients with esophageal cancer.
作者 杨合军 Yang Hejun(Department of Thoracic Surgery,the People's Hospital of Linzhang County,Handan City of Hebei Province 056600)
出处 《中国社区医师》 2017年第14期84-85,共2页 Chinese Community Doctors
关键词 食管癌 紫杉醇 吉非替尼 生存率 不良反应 Esophageal cancer Paclitaxel Gefitinib Survival rate Adverse reaction
  • 相关文献

参考文献10

二级参考文献111

  • 1张宜勤,陆进成,翟振宇,魏青.三维适形放疗食管癌临床研究的初步结果[J].中华放射肿瘤学杂志,2005,14(1):31-34. 被引量:115
  • 2Cunningham D,Allum WH,Stenning SP,菅鑫妍.手术期间化学疗法与单独手术治疗可切除的胃食管癌疗效比较[J].中国处方药,2006,5(8):59-60. 被引量:434
  • 3许泽苹,蔡舜吼,徐建芳.食管癌常规分割放疗同期化疗的临床观察[J].中华肿瘤防治杂志,2007,14(10):799-800. 被引量:9
  • 4周际昌.实用肿瘤内科学[M].北京:人民卫生出版社,2000:438.
  • 5Neuner G,Patel A,Suntharalingam M,et al. Chemoradiotherapy foresophageal cancer[ J]. Gastrointest Cancer Res,2009,3(2) :57 -65.
  • 6Koenig AM,Prenzel KL,Bogoevski D,et al. Strong impact of micm-metastatic tumor cell load in patients with esophageal carcinoma[J]. Ann Surg Oncol,2009,16:454 -462.
  • 7Natsugoe S, Matsumoto M, Okumura H,et al. Initial metastatic, in-cluding micrometastatic,sites of lymph nodes in esophageal squa-mous cell carcinoma[ J]. J Surg Oncol,2005,89:6 - 11.
  • 8Cooper JS, Guo MD, Herskovic A,et al. Chemoradiotherapy of lo-cally advanced esophageal cancer ; Long - term follow up of a pro-spective randomized trial(RTOG 85 -01 ) . Radiation Therapy On-cology Group[ J]. JAMA, 1999,281 (17) :1623 -1626.
  • 9Ohtsu A. Definitive chemoradiotherapy for T4 and/or lymphnode squamous cell carcinoma of the esophagus[ J]. J Clin Oncol,1999,17:2915 -2919.
  • 10Kelsey CR,Chino JP, Willett CG,et al. Paclitaxel - based chemo-radiotherapy in the treatment of patients with operable esophagealcancerf J]. Int J Radiat Oncol Biol Phys, 2007,69 ( 3 ) : 770 -776.

共引文献125

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部