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三种不同药物治疗老年高血压患者血栓前状态的对比研究 被引量:3

A comparative study on treating prethrombotic state in elderly hypertensive patients with 3 different medicines
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摘要 目的:观察三种不同药物治疗老年高血压患者血栓前状态的临床疗效。方法:将我院90例老年高血压患者随机分成三组,每组30例,A组服用中药痰瘀清方,B组在A组基础上口服西药苯磺酸氨氯地平,C组口服西药苯磺酸氨氯地平,治疗6周后,比较三组患者治疗前后收缩压、舒张压以及血浆PTS分子标志物水平变化情况。结果:A、B、C三组收缩压、舒张压均显著下降(P<0.05),A、B、C三组的血浆PTS分子标志物血管性血友病因子、D-二聚体和纤维蛋白原均有很好的改善(P<0.05);A组和B组老年高血压患者的血管性血友病因子、D-二聚体和纤维蛋白原与C组比较差异显著(P<0.05);B组与A组比较差异显著(P<0.05)。结论:中药痰瘀清方治疗老年高血压临床疗效显著,对血栓前状态具有很好的改善作用。 Objective:To observe efficacy of three different medicines on prethrombotic state in elderly hypertensive patients.Methods:90patients were divided into3groups.The group A was given the Tanyuqing prescription;the grorup B was given amlodipinebesylate more;the group C was given amlodipine besylate simply.Results:SBP and DBP in the group A,B,C were significantlydecreased(P<0.05);plasma PTS molecular markers von Willebrand factor,D-dimer and fibrinogen in the group A,B,C showed very goodimprovement(P<0.05);there were significant differences among the group A,B and C(P<0.05),and there was also a significant differencebetween the group B and A(P<0.05).Conclusion:The Tanyuqing prescription has obvious effects on hypertension in the elderly,and has agood effect on the prethrombotic state.
作者 许坚鸿
机构地区 普宁市中医医院
出处 《中医临床研究》 2017年第11期64-65,共2页 Clinical Journal Of Chinese Medicine
关键词 中药痰瘀清方 老年高血压 血栓前状态 临床疗效 The Tanyuqing prescription Elderly hypertension Prethrombotic state Clinical efficacy
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