摘要
目的探讨注射用兰索拉唑对比注射用泮托拉唑钠治疗上消化道出血的临床疗效。方法选取我院收治的112例消化性溃疡级急性糜烂出血性胃炎引起的上消化道出血的患者作为研究对象，随机分为试验组和对照组，每组均为56例。试验组患者给予兰索拉唑（30mg，静脉滴注，bid）治疗，对照组患者给予泮托拉唑（40mg，静脉滴注，bid）治疗。观察两组患者治疗有效率，治疗时间以及不良反应发生率。结果试验组患者和对照组患者的总有效率分别为98.2%和87.5%，试验组显著高于对照组（P＜0.05），试验组和对照组治疗时间为3-5天的患者占患者总数的75.0%和37.5%，试验组显著高于对照组（P＜0.05）。两组患者不良反应发生率均为1.79%，差异无统计学意义（P＞0.05）。结论对比泮托拉唑，兰索拉唑治疗上消化道出血可显著提高治疗有效率，显著缩短治疗时间，不良反应发生率低，值得临床推广。
Objective To evaluate the clinical efficacy of Lansoprazole IV compared with Pantoprazole IV treated with upper gastrointestinal bleeding.Method A total of112patients with upper gastrointestinal bleeding were randomly divided into control group and experience group.Each group included56patients.The experience group was given Lansoprazole(30mg,ivgtt,bid)and the control group was given Pantoprazole(40mg,ivgtt,bid).The clinical efficacy,treatment time and adverse reaction rate were compared between the two groups.Results The total clinical efficacy of the experience group and control group was98.2%and87.5%.The experience group was significantly higher than the control group(P<0.05).The number of the patients in the experience group and control group whose treatment time between3-5days was accounted for75.0%and37.5%of the total.The experience group was significantly higher than the control group(P<0.05).The adverse reaction rates were1.79%of the each group,which showed no significantly difference.Conclusion Compered with the Pantoprazole,Lansoprazole application in the patients with upper gastrointestinal bleeding can significantly improve the clinical efficacy and reduced the treatment time.It is worthy of promotion.
作者
丁金丽
Ding Jinli(The Affiliated Jiangning Hospital of Nanjing Medical University)
出处
《临床研究》
2017年第3期3-4,共2页
Clinical Research
关键词
兰索拉唑
上消化道出血
疗效观察
Lansoprazole
Upper gastrointestinal bleeding
Clinical efficacy observation
