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脑脊液引流联合尼莫地平治疗动脉瘤性蛛网膜下腔出血的疗效观察 被引量:2

Observation on the therapeutic effect of cerebrospinal fluid drainage combined with nimodipine in the treatment of aneurysmal subarachnoid hemorrhage
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摘要 目的:探讨腰大池持续引流联合尼莫地平治疗动脉瘤性蛛网膜下腔出血的临床疗效。方法:收治Hunt-Hess分级Ⅱ级以上动脉瘤性蛛网膜下腔出血患者67例,分为对照组和试验组。两组栓塞术后均给予钙离子拮抗剂,对照组行常规腰椎穿刺,试验组行腰大池持续引流。观察患者脑血管痉挛、再出血、脑积水发生率及3个月后格拉斯哥预后评分。结果:试验组脑血管痉挛、脑积水发生率低于对照组,格拉斯哥预后评分高于对照组,两组比较差异有统计学意义(P<0.05)。结论:腰大池引流可明显降低脑血管痉挛、脑积水发生率,而对降低再出血发生率作用不明显,总体上可明显改善动脉瘤性蛛网膜下腔患者的预后。 Objective:To investigate the clinical effect of continuous lumbar drainage combined with nimodipine in the treatmentof aneurysmal subarachnoid hemorrhage.Methods:67cases of Hunt-Hess gradeⅡor above aneurysmal subarachnoid hemorrhagepatients were divided into the control group and the experimental group.The two groups were treated with embolization of calciumantagonists.The control group underwent routine lumbar puncture.The experimental group were given continuous drainage oflumbar cistern.We observed patients with cerebrovascular spasm,hemorrhage,hydrocephalus incidence and after3monthsGlasgow outcome score.Results:The incidence of cerebral vasospasm and hydrocephalus in the experimental group was lower thanthat in the control group,and the score of Glasgow was higher than that of the control group.The difference was significant betweengroups(P<0.05).Conclusion:Lumbar cistern drainage can significantly reduce the incidence of cerebral vasospasm andhydrocephalus,but not significantly reduce the incidence of rebleeding,overall can significantly improve the prognosis of patientswith aneurysmal subarachnoid.
作者 张继全 Zhang Jiquan(Department of Neurosurgery,the People’s Hospital of Junan,Linyi City 276600)
出处 《中国社区医师》 2017年第20期80-81,共2页 Chinese Community Doctors
关键词 蛛网膜下腔出血 脑血管痉挛 腰大池持续引流 Subarachnoid hemorrhage Cerebral vasospasm Continuous drainage of lumbar cistern
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