摘要
目的:探讨单、双相抑郁患者睡眠呼吸紊乱与抑郁、焦虑症状的相关性。方法:收治抑郁症患者80例,按临床特点平分为单相组和双相组,进行睡眠和呼吸相关指标的检测,采用HAMA和HAMD评价两组患者的焦虑、抑郁现状;并分析睡眠呼吸紊乱与抑郁、焦虑的相关性。结果:双相组TST、SE、N-REM的StageⅢ、StageⅣ以及REM均显著少于单相组(P<0.05或P<0.01);双相组AHI、ODI和MODD均高于单相组,MSa O2和LSa O2低于单相组;双相组患者HAMD、HAMA评分均显著高于单相;HAMD、HAMA评分与TST、SE、N-REM的StageⅢ和Stage与Ⅳ、REM、MSa O2和LSa O2呈显著负相关,与AHI、ODI和MODD呈显著正相关(P<0.05)。结论:双相组患者睡眠呼吸紊乱情况较单相组严重,且患者的焦虑、抑郁程度与睡眠呼吸紊乱情况呈显著正相关。
Objective:To investigate the relationship between sleep disordered breathing and depression,anxiety in patients withsingle and bipolar depression.Methods:80patients with depression were selected.They were divided into the single group and thebipolar group on average.The sleep and respiratory related indicators were tested.The Hamilton Anxiety(HAMA)and HamiltonDepression(HAMD)were used to evaluate the status of anxiety and depression in the two groups,and the correlation between sleepdisordered breathing and depression,anxiety was analyzed.Results:The TST,SE,StageⅢ,Stage IV and REM of bipolar group weresignificantly less than the single group(P<0.05or P<0.01).The AHI,ODI and MODD of the bipolar group were higher than thoseof the single group,MSaO2and LSaO2were lower than the single group.HAMD,HAMA scores of the bipolar group weresignificantly higher than the single group.The HAMD and HAMA scores were significantly negatively correlated with TST,SE,StageⅢ,Stage IV,MSaO2,LSaO2and REM,and were significantly positively correlated with AHI,ODI and MODD(P<0.05).Conclusion:Compared with the single group,the sleep disordered breathing of the patients in the bipolar group was more severeand positively correlated with the degree of anxiety and depression.
作者
官长富
李德川
李先萍
Guan Changfu;Li Dechuan;Li Xianping(Department of Psychiatry,the Second People's Hospital of Neijiang City,Sichuan Province 641100)
出处
《中国社区医师》
2017年第20期107-108,共2页
Chinese Community Doctors
关键词
睡眠呼吸紊乱
焦虑
抑郁
相关性
Sleep-disordered breathing
Anxiety
Depression
Correlation
