摘要
目的探讨吻合器痔上黏膜环切术(PPH)日间手术时鞘内注射罗哌卡因的最佳剂量。方法选择2016年6月~2017年2月行吻合器痔上黏膜环切术日间手术的患者60例,随机分成三组,每组20例,分别鞘内注射罗哌卡因7.5、10、15mg,观察改良Bromage评分、达最大运动阻滞时间、运动阻滞持续时间、鞘内注射药物至可行走时间、鞘内注射药物至排尿时间、术中运动阻滞和术中镇痛。结果三组改良Bromage评分和达最大运动阻滞时间相近(P>0.05),至于运动阻滞持续时间、从鞘内注射药物至可行走时间以及从鞘内注射药物至排尿时间,则以15mg组最长,10mg组次之,7.5mg组最短,三组之间差异有统计学意义(P<0.05)。所有患者的术中运动阻滞和术中镇痛完全。结论在用于PPH日间手术时,鞘内注射罗哌卡因7.5mg的麻醉、镇痛质量和运动阻滞程度与10mg和15mg相似,可满足手术要求,且可明显缩短运动阻滞持续时间。
Objective To explore best dosage of ropivacaine by intrathecal injection in application of day surgery of procedure for prolapse and hemorrhoids(PPH).Methods60patients undergoing day surgery of procedure for prolapse and hemorrhoids from June2016to February2017were selected and they were randomly divided into three groups,with20in each.They were respectively given ropivacaine of7.5,10and15mg by intrathecal injection.Modified Bromage score,time for reaching maximum motor block,duration of motor block,time from drug by intrathecal injection to walking,time from drug by intrathecal injection to urination,intraoperative motor block and intraoperative analgesia were observed.Results Modified Bromage score and time for reaching maximum motor block in three groups were similar(P>0.05).Duration of motor block,time from drug by intrathecal injection to walking,time from drug by intrathecal injection to urination in the15mg group were the longest followed by the10mg group and the7.5mg group and those of the7.5mg group were the shortest.There were statistical difference between three groups(P<0.05).Intraoperative motor block and intraoperative analgesia of all patients were adequate.Conclusion When applied in day surgery of procedure for prolapse and hemorrhoids,anesthesia,quality of analgesia and degree of motor block of ropivacaine of7.5mg by intrathecal injection are similar to those of ropivacaine of10mg and15mg by intrathecal injection.It can fulfill the demands of procedure and significantly shorten the duration of motor block.
作者
岑燕遗
蓝岚
赵子良
CEN Yanyi;LAN Lan;ZHAO Ziliang(Department of Anesthesiology,First Affiliated Hospital to Guangzhou Medical University,Guangzhou,510120,China)
出处
《中国医药科学》
2017年第11期158-160,175,共4页
China Medicine And Pharmacy
关键词
鞘内
罗哌卡因
剂量
吻合器痔上黏膜环切术
Intrathecal
Ropivacaine
Dosage
Procedure for prolapse and hemorrhoids
