摘要
目的分析不同程度精索静脉曲张(VC)不育患者行精索静脉高位结扎术后精子DNA碎片的情况。方法不同程度VC不育患者57例。其中,诊断为2级患者27例,3级患者30例。所有患者行精索静脉高位结扎术前1个月及术后3个月检测并计算精子DNA碎片指数(DFI)。结果 57例VC不育患者均行腹腔镜双侧精索静脉高位结扎术。VC 2级和3级患者行手术治疗后精子DFI与术前比较均值降低,差异有统计学意义(P<0.05)。治疗前VC 2级和3级不育患者精子DFI比较差异无统计学意义(P>0.05);治疗后2级患者精子DFI低于3级患者(P<0.05),DFI改善情况优于3级患者(P<0.05)。结论腹腔镜精索静脉高位结扎术能够改善VC不育患者精子DNA碎片情况,对于2级患者效果更佳。
Objective To analyze the sperm DNA fragmentation in different degrees of varicocele(VC)infertility patients after high ligation of the spermatic vein.Methods There were57patients with differentdegrees of VC infertility patients.27patients had been diagnosed with level two VC,and30patients had beendiagnosed with level three VC.All patients’sperm DNA fragmentation index(DFI)were detected and calculated atpreoperative one month and postoperative three months.Results57VC infertility patients were all suffered fromlaparoscopic high ligation of the spermatic vein on both sides.There was no statistically difference on preoperativesperm DFI between level two and level three patients(P>0.05).All patients’sperm DFI were decreased afterlaparoscopic(P<0.05),and level two VC infertility patients had significant greater progress than level three patients(P<0.05).Conclusion Laparoscopic high ligation of the spermatic vein can effectively improve VC infertilitypatients sperm DFI.It would be better for level two VC infertility patients.
作者
曲仕浩
徐楗荧
罗英
陈取欣
Shi-hao Qu;Jian-ying Xu;Ying Luo;Qu-xin Chen(Department of Urology, Zhuhai Maternal and Children’s Hospital, Zhuhai, Guangdong 519000,China;Department of General Surgery, Yangjiang Maternal and Children’s Hospital,Yangjiang, Guangdong 529500, China)
出处
《中国内镜杂志》
北大核心
2017年第8期61-65,共5页
China Journal of Endoscopy
