摘要
目的应用高分辨率磁共振成像(high-resolution magnetic resonance image,HRMRI)技术研究症状性大脑中动脉粥样硬化性狭窄患者的管壁特征。材料与方法回顾性分析127例症状性大脑中动脉(middle cerebralartery,MCA)粥样硬化性狭窄患者的临床资料和影像学资料。根据扩散加权成像(diffusion weighted image,DWI)序列分为症状组和非症状组,比较两组患者的临床基线资料和管壁斑块情况(斑块分布、形态、信号)。结果糖尿病在两组中差异具有统计学意义(χ~2=23.446,P<0.001),症状组男性患者多于非症状组(χ~2=5.104,P=0.024)。年龄、高血压、高血脂、吸烟史、饮酒史在两组中差异无统计学意义(P<0.05)。127例患者中有110例有斑块,前壁斑块最多。症状组上壁斑块明显多于非症状组(χ~2=4.257,P=0.039),斑块表面不规则在两组中差异具有统计学意义(χ~2=8.087,P=0.004),症状组斑块高信号明显多于非症状组(χ~2=5.396,P=0.020)。结论 HRMRI可以评价症状性大脑中动脉粥样硬化性狭窄患者的管壁特征。
Objective:To evaluate the wall features of symptomatic atheroscleroticmiddle cerebral artery stenosis by using HRMRI.Materials and Methods:Onehundred and twenty-seven cases clinical data and image data about symptomaticatherosclerotic middle cerebral artery stenosis were analyzed.According to the DWIsequence,127cases were divided into symptomatic and asymptomatic group.Clinicaldata and wall features were compared between two groups(location,morphology,signal).Results:There was significantly difference between two groups in diabetes(χ2=23.446,P<0.001),male was more in symptomatic group than asymptomaticgroup(χ2=5.104,P=0.024),there was no significantly difference in two groups inage,hypertension,hyperlipidemia,smoke and drink(P>0.05).One hundred andten plaques in127cases,ventral plaque was the most.Superior plaque was more insymptomatic group than asymptomatic group(χ2=4.257,P=0.039),irregular surfacewas significant difference in two groups(χ2=8.087,P=0.004),hyper-intensity wasobvious difference in two groups(χ2=5.396,P=0.020).Conclusion:HRMRI couldevaluate the wall features of atherosclerotic middle cerebral artery.
作者
张连雪
杨本强
王子文
徐志华
段阳
ZHANG Lian-xue;YANG Ben-qiang;WANG Zi-wen;XU Zhi-hua;DUAN Yang(Department of Radiology, General Hospital of Shenyang Military Command, Shenyang 110016, China)
出处
《磁共振成像》
CAS
CSCD
2017年第8期567-571,共5页
Chinese Journal of Magnetic Resonance Imaging
基金
辽宁省自然科学基金指导计划项目(编号:201602768)~~
关键词
大脑中动脉
磁共振成像
斑块
动脉粥样硬化
糖尿病
Middle cerebral artery
Magnetic resonance imaging
Plaque,atherosclerotic
Diabetes mellitus
