摘要
药疹伴嗜酸性粒细胞增多和系统症状(DRESS)是一种严重的药物不良反应,以皮疹、发热、淋巴结肿大、嗜酸性粒细胞增多以及内脏受累为主要临床表现。本文报告1例在肾功能不全后服用致敏药物而出现以肢体无力及认知功能障碍为主要神经系统表现、以血管炎样影像学改变为特征的、且对激素治疗效果显著的DRESS综合征。
Drug rash with eosinophilia and systemic symptoms(DRESS)syndrome is a serious adverse drug reaction,characterized with rash,fever,lymphadenectasis,eosinophilia and visceral involvement.This article describes the clinical case of a patient with renal insufficiency after receiving sensitizing drugs,which resulted in limb weakness and cognitive impairment of center nervous system characterized by vasculitis imaging and responded well to glucocorticoid treatment-DRESS syndrome.
作者
廖海兵
徐琳
谢炳玓
鲍杰
宋毅军
LIAO Hai-bing;XU Lin;XIE Bing-di;BAO Jie;SONG Yi-jun(Department of Neurology,Tianjin Medical University General Hospital, Tianjin 300052, China;Department of Rehabilitation, Tianjin Medical University General Hospital, Tianjin 300052, China)
出处
《天津医药》
CAS
2017年第11期1208-1212,共5页
Tianjin Medical Journal
