摘要
目的探讨西洛他唑在预防下肢动脉硬化闭塞症支架植入术后再狭窄的应用。方法选取下肢动脉硬化闭塞症支架植入术后患者100例,随机分为西洛组和对照组,每组50例,对照组给予阿司匹林+氯吡格雷治疗,西洛组在此基础上给予西洛他唑治疗。结果西洛组和对照组患者术后再狭窄发生率及3、6个月支架处最小腔内直径水平明显低于术毕,但西洛组患者总支架处最小腔内直径下降值低于对照组(P<0.05),但两组患者出血事件发生率基本相同,差异无统计学意义。结论西洛他唑可进一步改善患者支架处最小腔内直径水平,有利于预防再狭窄发生,且具有良好的安全性。
Objective To discuss the application of cilostazol for preventing restenosis in lower extremity atherosclerotic occlusive disease stent implantation.Methods100patients with atherosclerotic occlusive disease were selected,all patients were randomly divided into cilos group and control group,50cases in each group,control group was given aspirin+clopidogrel treatment,cilos group on the basis was given cilostazol treatment.Results The3,6months legs of incidence of postoperative restenosis and minimal lumen diameter levels of cilos group were lower than those of end of operation,the minimal lumen diameter decline of the former was lower than the latter(P<0.05),but the incidence of bleeding events of two groups were the same.Conclusion Cilostazol can further improve minimal lumen diameter level of patients,it is helpful to the prevention of restenosis,and it has good security.
作者
邓晓涛
赵丽丽
Deng Xiao-tao;Zhao Li-li(Department of Vascular surgery, central hospital Yuncheng Shanxi, Yuncheng, Shanxi, 044000, China;Department of marketing Zhejiang yongning pharmaceutical co., LTD, Taizhou, Zhejiang, 318020, China)
出处
《当代医学》
2017年第35期42-44,共3页
Contemporary Medicine
关键词
西洛他唑
下肢动脉硬化闭塞症
支架植入术
再狭窄
Cilostazol
Lower extremity atherosclerotic occlusive disease
Stent implantation
Restenosis
