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帕瑞昔布钠结合耳穴压豆对锁骨骨折患者二次伤害性刺激的影响

Effect of parecoxib sodium combined with ear acupoint pressing beans on two times of nociceptive stimulation in patients with clavicular fracture
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摘要 目的分析帕瑞昔布钠结合耳穴压豆对锁骨骨折患者二次伤害性刺激的影响。方法选取金华市中心医院金西院区2015年7月~2017年4月收治的的50例锁骨骨折患者,随机分为实验组(n=25)与对照组(n=25)。实验组与对照组患者均进行常规手术治疗,麻醉方式均为颈丛加臂丛阻滞麻醉。实验组在此基础上给予帕瑞昔布钠结合耳穴压豆。比较分析实验组与对照组患者的围术期不良反应、心率(HR)、平均动脉压(MAP)及视觉疼痛评分(VAS)。结果治疗后,实验组心率、MAP、VAS评分均明显低于对照组,2组比较差异有统计学意义(P<0.05)。实验组不良反应发生率为16.0%,显著高于对照组发生率为40.0%,比较差异有统计学意义(P<0.05)。结论帕瑞昔布钠结合耳穴压豆可显著降低锁骨骨折患者二次伤害性刺激,缓解患者疼痛,降低不良反应发生率。 Objective To study the analysis of parecoxib sodium combined with auricular plaster therapy in patients with two noxious stimulation effect on the fracture of the clavicle.Methods50cases of clavicle fracture patients from July2015to April2017were divided into experimental group(n=25)and the control group(n=25).The experimental group and the control group were treated with routine surgery,anesthesia methods were cervical plexus combined with brachial plexus block anesthesia.On the basis of the experimental group received parecoxib sodium combined with auricular plaster therapy.The perioperative adverse reactions,heart rate(HR),mean arterial pressure(MAP)and visual pain score(VAS)were compared and analyzed between the experimental group and the control group.Results After treatment,the HR,MAP and VAS score of the experimental group were all significantly lower than that of the control group(P<0.05).The incidence of adverse reactions in the experimental group was16%,significantly higher than that in the control group(40%),and the difference was statistically significant(P<0.05).Conclusion Parecoxib sodium combined with auricular plaster therapy can significantly reduce the clavicle fracture patients with two times of noxious stimulation,relieve the pain of patients,reduce the incidence of adverse reaction.
作者 黄建林 张贤杰 HUANG Jian-lin;ZHANG Xian-jie(Department of Orthopedics, Jinxi Hospital of Jinhua Central Hospital, Jinhua 321075, China)
出处 《中国生化药物杂志》 CAS 2017年第12期42-43,共2页 Chinese Journal of Biochemical Pharmaceutics
关键词 帕瑞昔布钠 耳穴压豆 锁骨骨折 二次伤害性刺激 parecoxib sodium auricular plaster therapy clavicular fracture two nociceptive stimulation
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