摘要
目的观察胃溃疡患者接受三联疗法治疗的效果及血清炎症因子变化情况。方法选取宁夏大学医保中心2016年1月～2017年1月收治的胃溃疡患者100例，随机分为2组，每组50例。对照组采取单药治疗，观察组采用三联疗法治疗。比较2组治疗效果、血清炎症因子变化及复发情况。结果观察组胃溃疡患者治疗总有效率为98.00%，显著高于对照组的78.00%（P＜0.05）。观察组治疗后IL-6水平（131.06±1.74）ng/L，对照组为（183.64±1.33）ng/L，差异有统计学意义（P＜0.05）。观察组胃溃疡患者复发率为2.00%，明显低于对照组20.00%（P＜0.05）。结论对胃溃疡患者采用三联疗法进行治疗，具有十分显著的效果，且能够改善其血清炎症因子水平，降低复发率，值得研究。
Objective To observe the effect of triple therapy in patients with gastric ulcer and the changes of serum inflammatory factors.Methods100patients with gastric ulcer admitted in our hospital from January2016to January2017were randomly divided into two groups,50cases in each group.The control group was treated with single drug,and the observation group was treated with triple therapy.The treatment effect,serum inflammatory factors and recurrence were compared between the two groups.Results The total effective rate of the observation group was98%,which was significantly higher than78%of the control group(P<0.05).After treatment,the level of IL-6in the observation group was(131.06±1.74)ng/L,and that in the control group was(183.64±1.33)ng/L,the difference was statistically significant(P<0.05).The recurrence rate of gastric ulcer in observation group was2.00%,which was significantly lower than20.00%of control group(P<0.05).Conclusion The treatment of gastric ulcer patients with triple therapy,has a very significant effect,and can improve the level of serum inflammatory factors,reduce the recurrence rate.
作者
张建琴
王剑君
ZHANG Jian-qin;WANG Jian-jun(Department of Internal Medicine, Ningxia University Medical Center, Yinchuan 750012, China;Department of Internal Medicine, Tongtian Town, Jinfeng District, Yinchuan City, Yinchuan 750002, China)
出处
《中国生化药物杂志》
CAS
2017年第12期132-133,共2页
Chinese Journal of Biochemical Pharmaceutics
关键词
胃溃疡
三联疗法
血清炎症因子
gastric ulcer
triple therapy
serum inflammatory factor
