摘要
目的:探讨乳腺癌保乳术后同步放化疗对患者机体免疫力的影响。方法:选取2015年1月-2016年3月期间在我院行保乳术的乳腺癌患者,共计74例,将其随机分为对照组与观察组,每组37例。对照组患者术后采用放疗方式治疗,而观察组患者术后同步放化疗,对比两组患者临床疗效,同时对比患者外周血CD3+、CD4+、CD8+细胞百分率变化情况。结果:观察组患者局部复发率为8.11%,明显低于对照组的24.32%,差异对比明显,具有统计学意义,P<0.05。两组患者不良反应发生率、外周血CD3+、CD4+、CD8+百分率之间差异不够明显,不具有统计学意义,P>0.05。结论:通过乳腺癌保乳术后同步放化疗,能够明显降低患者局部复发率,同时安全性、可靠性较高,在临床中值得大力推广。
Objective:To investigate the effects of radiotherapy and chemotherapy on the immunity of patients with breast cancer after breast-conserving surgery.Methods:74patients were randomly divided into the control group and observation group,37cases in each.The control group was treated by radiotherapy after surgery;the observation group was treated by radiotherapy and chemotherapy after surgery.The effects and changes of CD3+,CD4+and CD8+cells were compared.Results:The local recurrence rate was8.11%in the observation group,and significantly lower than24.32%in the control group,with a statistically significant difference(P<0.05).There were no significant differences in the incidence of adverse reactions,the percentage of CD3+,CD4+and CD8+cells between groups(P>0.05).Conclusion:Radiotherapy and chemotherapy after surgery can significantly reduce the local recurrence rate,with higher safety and reliability,is worthy of population.
出处
《中医临床研究》
2017年第31期119-120,共2页
Clinical Journal Of Chinese Medicine
关键词
乳腺癌保乳术
放化疗
机体免疫力
The breast-conserving surgery
Radiotherapy and chemotherapy
Body immunity
