摘要
目的评价血细胞比容(HCT)、维生素C(Vc)和半乳糖等干扰因素对3种便携式血糖仪的影响,为临床选择合适的血糖仪提供一定参考。方法选取该院检验科肝素锂抗凝的静脉血标本20份用于血糖仪准确度验证,选取2名健康志愿者的空腹静脉全血标本各5份用于干扰物试验,参考罗氏C501全自动生化分析仪的检测结果,对Nova StatStrip Xpress血糖仪、拜安进血糖仪、罗氏卓越血糖仪进行准确度验证,评价HCT、Vc和半乳糖对以上3种便携式血糖仪检测结果的影响。结果 Nova StatStrip Xpress血糖仪和罗氏卓越血糖仪检测准确度均符合ISO15197∶2013标准要求,拜安进血糖仪检测准确度仅符合ISO15197∶2003标准要求。在不同水平HCT、Vc、半乳糖干扰下,Nova StatStrip Xpress血糖仪检测结果均符合ISO15197∶2013标准要求;拜安进血糖仪检测低浓度血糖时受到10mg/dL Vc干扰,其余检测结果均符合ISO15197∶2003标准要求;罗氏卓越血糖仪对HCT的抗干扰性能符合ISO15197∶2013标准要求,但受Vc和半乳糖干扰较大。结论 3种便携式血糖仪的准确度和抗干扰性能不同,临床应根据患者实际情况选择合适的血糖仪,确保血糖检测的准确性。
Objective To evaluate the influence of hematocrit(HCT),vitamin C(Vc)and galactose on three portable blood glucose meters to provide some reference for clinical selection of appropriate blood glucose meter.Methods20heparin anticoagulant venous blood samples in the clinical laboratory department of Nanfang Hospital were selected for verifying the accuracy of blood glucose meter.2healthy volunteers were selected for collecting5whole blood samples in interferent test.Referring to the detection results of Roche automatic biochemical analyzer,the Nova StatStrip Xpress glucometer,Bayer Contour Plus glucometer and Roche Accu-chek Performa blood glucose meter were performed the accuracy verification.The influence of HCT,Vc and galactose on the detection results of above three portable blood glucose meters were evaluated.Results The detection accuracy of Nova StatStrip Xpress and the Roche Accu-Chek glucometers all conformed to the requirements of ISO15197∶2013standards.The detection accuracy of Bayer Contour Plus glucometer only conformed to the requirements of ISO15197∶2003standards.Under the interference of different levels of HCT,Vc and galactose,the detection results of Nova StatStrip Xpress glucometer conformed to the requirements of ISO15197:2013standards;when detecting low concentration of blood glucose,the Bayer Contour Plus glucometer was interfered by10mg/dL Vc,and other detection results conformed to the requirements of ISO15197∶2003standards;the anti-interference performance of Roche Accu-chek Performa glucometer conformed to the requirements of ISO15197∶2013standards,but the Vc and galactose interference was relatively great.Conclusion The accuracy and anti-interference performance have difference among the three portable blood glucose meters.Clinic should select suitable blood glucose meter according to the actual situation of the patients to ensure the accuracy of blood glucose detection.
作者
孙德华
毛欣茹
郑磊
艾育华
李文源
SUN Dehua;MAO Xinru;ZHENG Lei;AI Yuhua;LI Wenyuan(Department of Clinical Laboratory,Nanfang Hospital,Southern Medical University,Guangzhou,Guangdong 510515,China;Department of Information,Nanfang Hospital,Southern Medical University,Guangzhou,Guangdong 510515,China;General Administration Office,Nanfang Hospital,Southern Medical University,Guangzhou,Guangdong 510515,China)
出处
《国际检验医学杂志》
CAS
2018年第6期651-654,657,共5页
International Journal of Laboratory Medicine
基金
2016年广东省级财政资金互联网+领域项目[粤财工(2016)187号]
2013年度广东省信息产业发展专项物联网应用扶持项目[粤经信信息函(2014)975号]
