摘要
目的探讨全结肠系膜切除术(CME)与传统手术治疗结肠癌对患者远期疗效及生存质量的影响。方法回顾性分析于2012年3月至2014年3月期间收治的96例结肠癌患者的临床资料,按照手术方式的不同分为研究组(n=48)与对照组(n=48),研究组患者行CME治疗,对照组患者行传统根治术治疗,比较两组远期疗效、手术相关指标、淋巴结清扫情况、生存质量及并发症发生情况。结果研究组远期治疗优良率为91.67%,明显高于对照组的75.00%,差异具有统计学意义(P<0.05);研究组手术时间、出血量、引流量、术后排气时间及住院时间均低于对照组,而阳性淋巴结、左半结肠淋巴结、右半结肠淋巴结及淋巴结平均清扫数量均高于对照组,差异具有统计学意义(P<0.05);术后,研究组心理功能、生理机能、社会功能及总体健康评分均明显高于术前与对照组;研究组并发症总发生率为4.17%,低于对照组25.00%,差异均有统计学意义(P<0.05)。结论 CME治疗结肠癌的远期疗效确切,可显著提高淋巴结清扫数量,同时改善患者生存质量,相比于传统根治术效果更好,值得推广。
Objective To investigate the effect of complete mesocolic excision(CME)versus traditional surgery on long-term efficacy and survival quality in patients with colon cancer.Methods The clinical data of 96 patients with colon cancer in our hospital from March 2012 to March 2014 were retrospectively analyzed,and they were divided into research group(n=48)and control group(n=48)by surgical methods.Research group was given CME,while control group was treated with traditional surgery.The long-term efficacy,surgical indexes,lymph node dissection,survival quality and complications were compared between the two groups.Results The long-term excellent effective rate of research group was 91.67%,which was higher than 75.00%in control group(P<0.05).The operation time,bleeding volume,drainage volume,postoperative exhaust time and hospital stays in research group were lower than those in control group,but positive lymph node,left-semicolon lymph node,right-semicolon lymph node,average lymph node dissection amount in observation group were higher than those in control group(P<0.05).After surgery,the scores of mental function,physiological function,social function,overall heath in research group were higher than those before surgery and control group;The total incidence of complications in research group was 4.17%,which was lower than 25.00%in control group(P<0.05).Conclusion CME in treatment of colon cancer has effective long-term efficacy,it can increase lymph node dissection amount and improve survival quality.Compared with traditional surgery,CME has better curative effects and is worthy of promotion.
作者
苏洲
赵豹
李振
SU Zhou;ZHAO Bao;LI Zhen(Department of Gastrointestinal Surgery,Wanbei Coal-Electricity Group General Hospital,Suzhou Anhui 234000,China)
出处
《临床和实验医学杂志》
2018年第6期644-647,共4页
Journal of Clinical and Experimental Medicine
关键词
结肠癌
全结肠系膜切除
传统手术
远期疗效
生存质量
Colon cancer
Complete mesocolic excision
Traditional surgery
Long-term efficacy
Survival quality
