摘要
目的探究头孢曲松钠联合醒脑静对新生儿化脓性脑膜炎患儿脑脊液生化指标的影响。方法选择我院2015年3月~2016年9月收治的新生儿化脓性脑膜炎患儿86例为研究对象,依入院时间分为观察组和对照组,各43例。对照组在接受常规及对症治疗基础上使用头孢曲松钠,在对照组基础上给予观察组醒脑静。将两组患儿治疗后脑脊液生化指标、体征改善、住院时间、并发症发生情况进行对比。结果治疗后,观察组患儿蛋白浓度、白细胞计数、糖浓度水平均优于对照组,差异显著(P<0.05);观察组体温恢复时间、脑脊液WBC计数正常时间、住院时间均明显短于对照组,差异显著(P<0.05);两组并发症发生情况对比,差异不显著(P>0.05)。结论头孢曲松钠联合醒脑静治疗新生儿化脓性脑膜炎,可显著优化患儿脑脊液生化指标,安全性好。
Objective To investigate the effect of ceftriaxone sodium combined with Xingnaojing on cerebrospinal fluid biochemical indexes of newborn with neonatal purulent meningitis.Methods A total of 86 cases of neonatal purulent meningitis admitted to our hospital from March 2015 to September 2016 were enrolled into this study.The patients were divided into observation group and control group according to the admission time with 43 cases in each group.The control group was treated with ceftriaxone sodium on the basis of routine and symptomatic treatment.The observation group was additionally given Xingnaojing on the basis of control group.The biochemical indexes,improvement of signs,hospitalization time and complication were compared between the two groups after treatment.Results After treatment,the protein concentration,white blood cell count and sugar concentration in the observation group were significantly higher than those in the control group,and the difference was statistically different(P<0.05).The temperature recovery time,the cerebrospinal fluid WBC normal time and the time of hospitalization was significantly shorter than that of control group,the difference was statistically significant(P<0.05).when the incidence of complications was compared between the two groups,there was no significant difference(P>0.05).Conclusion In the treatment of newborn with neonatal purulent meningitis,ceftriaxone combined with Xingnaojing can significantly optimize the biochemical indexes of cerebrospinal fluid of newborn,and the safety is good.
作者
钱东星
郑柳萍
郑田华
QIAN Dong-xing;ZHENG Liu-ping;ZHENG Tian-hua(Department of Neonatology,Queshan County People’s Hospital,Queshan,Henna,463200,China)
出处
《临床研究》
2018年第2期35-36,共2页
Clinical Research
