摘要
目的探讨慢性阻塞性肺疾病(COPD)流行病学调查及防控措施。方法选择2015年3月-2017年12月本地区500名40岁以上人群作为研究对象,对其行肺功能测定,根据检查结果将患者分为COPD组(44例)和非COPD组(456例)。采用医院自拟问卷调查表对两组一般资料进行调查,包括:吸烟、被动吸烟、粉尘接触史、慢性阻塞性肺疾病史、疫苗接种史、家族呼吸系统病史、年龄、性别,对上述危险因素进行单因素及多因素Logistic回归分析,针对危险因素制定有效的措施进行干预,降低COPD发生率。结果 500例筛查患者中,经肺功能测定44例最终确诊为COPD,确诊率为8.8%。其中,疾病严重程度排在前两位的为Ⅰ级、Ⅱ级,分别占47.73%、22.73%;单因素分析结果表明:COPD发病率与性别、疫苗接触史、体质指数(BMI)水平无明显相关(P<0.05),与吸烟、被动吸烟、粉尘接触史、慢性阻塞性肺疾病史、家族呼吸系统病史关系密切(P<0.05);多因素Logistic回归分析表明:COPD发病率与吸烟、被动吸烟、粉尘接触史、COPD史、家族呼吸系统病史关系密切(P<0.05)。结论 COPD发病率相对较高,影响因素较多,应根据危险因素制定有效的措施进行干预,以降低疾病发生率。
Objective To explore the results of epidemiological investigations and prevention measures of chronic obstructive pulmonary disease.Methods Five hundred people over the age of 40 in this region were selected as subjects between March 2015 and December 2017.Pulmonary function tests were performed on the patients.According to the test results,they were divided into the chronic obstructive pulmonary disease group(n=44)and the non-chronic obstructive pulmonary disease group(n=456).The general information of the two groups was collected via a self-designed questionnaire involving smoking,second-hand smoking,dust exposure history,history of chronic obstructive pulmonary disease,vaccination history,family history of respiratory disease,age and gender.Univariate and multivariate logistic regression analysis was carried out on these risk factors,and effective interventions were enforced in order to reduce the incidence of chronic obstructive pulmonary disease.Results Among the 500 cases,there were 44 cases of chronic obstructive pulmonary disease confirmed by lung function test,and the rate of diagnosis was 8.8%.Among them,grade I and II were the most severe of the disease,which accounted for 47.73%and 22.73%,respectively.Univariate results showed that there was no significant correlation between the incidence of chronic obstructive pulmonary disease and gender,vaccine exposure history and body mass index(BMI)(P<0.05).The incidence of chronic obstructive pulmonary disease was closely related to smoking,second-hand smoking,dust exposure history,chronic obstructive pulmonary disease history and family respiratory disease history(P<0.05).Multivariate logistic regression analysis showed that the incidence of chronic obstructive pulmonary disease was closely related to smoking,second-hand smoking,dust exposure history,chronic obstructive pulmonary disease history and family respiratory system disease history(P<0.05).Conclusion The incidence of chronic obstructive pulmonary disease is relatively high,and is influenced by many factors.Therefore,effective measures should be taken according to risk factors so as to reduce the incidence of the disease.
作者
易方莲
易松涛
YI Fanglian;YI Songtao(Center for Disease Control and Prevention of Yibin,Yibin Sichuan 644000,China)
出处
《解放军预防医学杂志》
CAS
2018年第2期171-173,180,共4页
Journal of Preventive Medicine of Chinese People's Liberation Army
基金
国家自然科学基金(No.81450095)
关键词
慢性阻塞性肺疾病
流行病学调查
防控措施
危险因素
chronic obstructive pulmonary disease
epidemiological investigation
prevention and control meas鄄ures
risk factors
