摘要
目的:研究经尿道1 470 nm激光前列腺剜除术和经尿道前列腺电切术(TURP)治疗大体积良性前列腺增生(BPH)的效果,为临床提供可靠依据。方法:选取本院2014年1月-2017年2月收治的大体积BPH患者128例作为研究对象,按照随机数字表法将其分为试验组与参照组,每组各64例。试验组采用经尿道1 470 nm激光前列腺剜除术,参照组采用TURP治疗。比较两组术中出血量、术后膀胱持续冲洗时间、手术时间、导尿管留置时间及住院时间;比较术前与术后6个月患者的残余尿量(PVRU)、生命质量评分(QOL)、最大尿流率(Qmax)、国际前列腺症状评分(IPSS);比较两组术后并发症。结果:试验组的手术时间、术中出血量、术后膀胱持续冲洗时间、尿道管留置时间以及住院时间均低于参照组(P<0.05);术后6个月,两组PVRU、QOL、Qmax及IPSS均低于术前(P<0.05),但两组比较差异均无统计学意义(P>0.05);试验组并发症发生率为1.56%(1/64),低于参照组的21.88%(14/64),比较差异有统计学意义(χ~2=12.762,P=0.000)。结论:采用经尿道1 470 nm激光前列腺剜除术和TURP治疗大体积BPH患者均有显著的治疗效果,但与TURP治疗相比较,经尿道1 470 nm激光前列腺剜除术具有出血量少、恢复迅速、并发症发生率较低等优势。
Objective:To study the effect of 1 470 nm laser transurethral enucleation of the prostate and transurethral resection of the prostate(TURP)treatment of large volume benign prostatic hyperplasia(BPH),to provide a reliable basis for clinical practice.Method:A total of 128 patients with large volume BPH in our hospital from January 2014 to February 2017 were selected.According to the random number table method,they were divided into experimental group and reference group,64 cases in each group.The experimental group was treated with 1 470 nm laser transurethral enucleation of the prostate,and reference group treated by TURP.The amount of intraoperative bleeding,duration of postoperative bladder irrigation,operation time,indwelling time of urethral catheter and hospitalization time between two groups were compared,the residual urine volume(PVRU),quality of life score(QOL),maximum urinary flow rate(Qmax)and international prostate symptom score(IPSS)before and 6 months after operation between two groups were compared,the postoperative complications in two groups were compared.Result:The amount of intraoperative bleeding,duration of postoperative bladder irrigation,operation time,indwelling time of urethral catheter and hospitalization time in experimental group were all lower than those of reference group(P<0.05).After operation 6 months,the PVRU,QOL,Qmax and IPSS in two groups were all lower than those of before operation(P<0.05),but the two groups were compared,the differences were not statistically significant(P>0.05).The incidence of complications in experimental group was 1.56%(1/64),which was lower than 21.88%(14/64)of reference group,the difference was statistically significant(χ2=12.762,P=0.000).Conclusion:Both 1 470 nm laser transurethral enucleation of the prostate and TURP have significant therapeutic effects in the treatment of large volume BPH,however,compared with the TURP treatment,1 470 nm laser transurethral enucleation of the prostate has the advantages of less bleeding,rapid recovery and low incidence of complications.
作者
冯海航
梁高照
汪清
FENG Haihang;LIANG Gaozhao;WANG Qing(Shenzhen Baoan District People’s Hospital,Shenzhen 518101,China)
出处
《中国医学创新》
CAS
2018年第4期65-68,共4页
Medical Innovation of China
