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氯吡格雷治疗冠心病心力衰竭患者30例临床观察 被引量:1

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摘要 目的探讨氯吡格雷治疗冠心病(coronary heart disease,CHD)心力衰竭的临床效果及安全性。方法收集60例CHD心力衰竭患者,随机数字表法分为观察组和对照组,各30例,除基础治疗外,对照组给予阿司匹林治疗,观察组给予氯吡格雷治疗,比较两组患者的临床治疗效果及不良反应发生情况。结果治疗后观察组患者血小板凝聚率(31.12±12.24)%低于对照组(45.81±12.27)%,活化部分凝血活酶时间(APTT)及左心室射血分数(LVEF)水平高于对照组,差异均有统计学意义(P<0.05);观察组患者治疗总有效率93.33%高于对照组73.33%,观察组不良反应发生率10.0%低于对照组26.7%,差异均有统计学意义(P<0.05)。结论氯吡格雷治疗CHD心力衰竭疗效确切,具有较好的抗血小板凝聚作用,不良反应少。
作者 胡光环
出处 《河南医学高等专科学校学报》 2018年第1期23-24,共2页 Journal of Henan Medical College
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