摘要
目的对热疗联合放疗治疗局部晚期肺鳞癌的临床疗效进行讨论。方法将利辛县人民医院收治的40例局部晚期肺鳞癌患者(收治时间为2016年6月—2017年6月)根据硬币法分为单一组和联合组。单一组20例患者给予放疗的方法进行治疗,联合组患者在此基础上给予联合热疗的方法进行治疗,对其治疗效果及不良反应发生率进行比较。结果 (1)联合组患者治疗总有效率85.0%明显优于单一组患者50.0%,数据差异有统计学意义(χ2=5.584,P<0.05)。(2)联合组患者不良反应发生率35.0%比单一组患者70.0%低,经统计学分析后发现差异有统计学意义(χ2=4.912,P<0.05)。(3)联合组生活质量评分明显比单一组患者生活质量评分高,经统计学分析后发现有统计学意义(t=7.152、4.539、6.919、5.820、4.904、10.689,P<0.05)。结论热疗联合放疗治疗局部晚期肺鳞癌有效果好、安全性高的优势,极大的提高了患者的生活质量,值得在临床中推广。
Objective To discuss the clinical curative effect of hyperthermia combined with radiotherapy in the local advanced pulmonary squamous cell carcinoma.Methods 40 cases of patients with local advanced squamous cell carcinoma admitted and treated in our hospital from June 2016 to June 2017 were selected and divided into two groups with 20 cases in each,the single group were treated with radiotherapy,while the combined group used the hyperthermia combined with radiotherapy,and the treatment effect and incidence rate of adverse reactions were compared between the two groups.Results The total treatment effective rate in the combined group was obviously better than that in the single group,(85.0%vs 50.0%),and the difference was statistically significant,(χ2==5.584,P<0.05),and the incidence rate of adverse reactions in the combined group was lower than that in the single group,(35.0%vs 70.0%),and the difference was statistically significant,(χ2=4.912,P<0.05),and the quality of life score in the combined group was higher than that in the single group,and the difference was statistically significant,(t=7.152,4.539,6.919,5.820,4.904,10.689,P<0.05).Conclusion The effect of hyperthermia combined with radiotherapy in the local advanced pulmonary squamous cell carcinoma is good with high safety,which can greatly improve the quality of life of patients,and it is worth clinical promotion.
作者
赵东
ZHAO Dong(Department of Tumor Radiotherapy,Lixin People’s Hospital,Lixin,Anhui Province,236700 China)
出处
《系统医学》
2017年第23期112-114,共3页
Systems Medicine
关键词
热疗
放疗
局部晚期肺鳞癌
临床疗效
Hyperthermia
Radiotherapy
Local advanced squamous cell carcinoma
Clinical curative effect
