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饮食干预联合硫普罗宁治疗酒精肝临床研究 被引量:4

Clinical Study on Dieting Intervention Combined with Tiopronin in Treatment of Alcohol Liver
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摘要 目的探析饮食干预与硫普罗宁联合在酒精肝疾病治疗中的临床运用效果。方法抽取2014年7月—2017年7月该院所接收的90例酒精肝患者作为研究对象,按就诊前后顺序分成常规组与联合组,常规组采取硫普罗宁治疗,联合组采取饮食干预+硫普罗宁;比较两组患者的疾病治疗情况。结果联合组患者治疗后的总有效率(93.3%)显著高于常规组(75.6%),差异有统计学意义(P<0.05);联合组患者治疗后的ALT、AST、γ-GT、TC、TG分别为(20.68±8.36)U/L、(20.14±5.67)U/L、(45.97±8.16)U/L、(3.51±0.58)mmol/L、(1.15±0.18)mmol/L,常规组分别为(28.66±7.54)U/L、(25.31±6.87)U/L、(60.25±7.67)U/L、(5.79±0.42)mmol/L、(2.66±0.14)mmol/L。组间各指标相比差异有统计学意义(P<0.05)。结论对酒精肝患者采取饮食干预与硫普罗宁治疗,效果甚佳,值得在临床上推广。 Objective To analyze the clinical application effect of dieting intervention combined with tiopronin in treatment of alcohol liver.Methods 90 cases of patients with alcohol liver admitted and treated in our hospital from July 2014 to July 2017 were selected and divided into the routine group and the combined group according to the diagnosis order,the routine group were treated with tiopronin,while the combined group were treated with dieting intervention combined with tiopronin,and the disease treatment situation was compared between the two groups.Results The total treatment effective rate in the combined group was obviously higher than that in the routine group(93.3%vs 75.6%),and the difference was statically significant(P<0.05),after treatment,the ALT,AST,γ-GT,TC,TG in the combined group and in the routine group were respectively(20.68±8.36)U/L,(20.14±5.67)U/L,(45.97±8.16)U/L,(3.51±0.58)mmol/L,(1.15±0.18)mmol/L and(28.66±7.54)U/L,(25.31±6.87)U/L,(60.25±7.67)U/L,(5.79±0.42)mmol/L,(2.66±0.14)mmol/L,and the differences were statistically significant(P<0.05).Conclusion The effect of dieting intervention combined with tiopronin in treatment of alcohol liver is good,which is worth clinical promotion.
作者 赵星 ZHAO Xing(Digestive System Department,Bayan Nur Hospital,Bayan Nur,Inner Mongolia,015000 China)
出处 《系统医学》 2017年第22期51-53,共3页 Systems Medicine
关键词 酒精肝 饮食干预 硫普罗宁 Alcohol liver Dieting intervention Tiopronin
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