摘要
目的探讨妊娠期甲状腺功能减退对母体血糖、血脂变化及母婴结局的影响。方法选择2016年4月—2017年4月该院收治妊娠期甲状腺功能减低患者80例,按照是否合并妊娠期甲状腺功能减退者分为两组(疾病组与正常组),各40例,疾病组为确诊妊娠期甲状腺功能减退者,正常组为正常体检者,比较两组新生儿1 min及5 min Apgar评分变化情况,统计两组分娩后开始性生活及规律性生活时间,入组者血脂与血糖变化。结果疾病组新生儿1 min Apgar评分为(6.4±0.2)分,显著低于正常组的(8.5±0.3)分(t=36.845,P<0.05),5 min Apgar评分为(6.8±0.2)分显著低于正常组的(9.0±0.3)分(t=38.599,P<0.05),疾病组开始性生活时间为(2.8±0.3)月,晚于正常组的(1.5±0.1)月(t=28.018,P<0.05),恢复规律性生活时间为(4.8±0.5)月,晚于正常组的(3.6±0.2)月(t=15.360,P<0.05),观察组TC、TG、LDL-C水平分别为(6.0±0.2)mmol/L、(2.3±0.2)mmol/L和(3.6±0.3)mmol/L,均高于对照组(4.5±0.1)mmol/L、(1.4±0.1)mmol/L和(2.3±0.2)mmol/L(t=42.360,25.518,210.494,P<0.05),血糖为(3.6±0.2)mmol/L,低于对照组的(5.9±0.5)mmol/L(t=17.685,P<0.05)。结论妊娠期甲状腺功能减退者,存在明显的血糖血脂代谢异常,其容易出现新生儿窒息,且产妇产后容易出现性生活质量下降。
Objective To study the effect of hypothyroidism during the pregnancy on the maternal blood glucose,blood liquid change and maternal and infant outcome.Methods 80 cases of patients with hypothyroidism admitted and treated in our hospital from April 2016 to April 2017 were selected and divided into two groups with 40 cases in each according to whether the patients were complicated by hypothyroidism or not(disease group and normal group),and the disease group were confirmed with hypothyroidism patients,while the normal group were the normal physical examination persons,and the 1 min and 5 min Apgar score changes of the two groups were compared and the sexy life starting time and regularity life time and changes of blood liquid and blood glucose of the two groups were counted after delivery.Results The 1min Apgar score of newborns in the disease group was obviously lower than that in the normal group,[(6.4±0.2)points vs(8.5±0.3)points](t=36.845,P<0.05),and 5 min Apgar score was obviously lower than that in the normal group,[(6.8±0.2)points vs(9.0±0.3)points](t=38.599,P<0.05),and the sex life starting time in the normal group was later than that in the normal group,[(2.8±0.3)months vs(1.5±0.1)months](t=28.018,P<0.05),and the regular sex life recovery time was later than that in the normal group,[(4.8±0.5)months vs(3.6±0.2)months](t=15.360,P<0.05),and the TC,TG,LDL-C levels in the observation group were higher than those in the control group[(6.0±0.2)mmol/L,(2.3±0.2)mmol/L,(3.6±0.3)mmol/L vs(4.5±0.1)mmol/L,(1.4±0.1)mmol/L,(2.3±0.2)mmol/L](t=42.360,25.518,210.494,P<0.05),and the blood glucose was lower than that in the control group[(3.6±0.2)mmol/L vs(5.9±0.5)mmol/L](t=17.685,P<0.05).Conclusion The hypothyroidism patients during pregnancy have obvious metabolic abnormalities of blood glucose and blood liquid,and the asphyxia neonatorum is easy to occur,and the decrease of the sex life quality is easy to occur after delivery.
作者
许雯静
马宁娜
XU Wen-jing;MA Ning-na(Department of Physical Examination,Akesu Maternal and Child Healthcare Hospital,Akesu,Xinjiang,843000 China)
出处
《系统医学》
2017年第17期104-106,共3页
Systems Medicine
关键词
妊娠期甲状腺功能减退
血糖
血脂
母婴结局
Hypothyroidism during pregnancy
Blood glucose
Blood liquid
Maternal and infant outcome
