摘要
目的:分析酒精依赖患者血液生化水平的变化。方法:选取60例酒精依赖患者设为酒依赖组,另选取健康人群60例作为对照组。采用日立7600全自动生化分析仪检测并比较两组血液生化指标。结果:酒依赖组的血钾、钙、磷、镁水平明显低于对照组(P<0.05),丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)、碱性磷酸酶(ALP)、谷氨酰转肽酶(GGT)、肌酸激酶(CK)、乳酸脱氢酶(LDH)等血清酶类指标及总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL)、载脂蛋白B(Apro B)水平均明显高于对照组(P<0.05),高密度脂蛋白(HDL)、载脂蛋白A(Apro A)、总蛋白(TP)、白蛋白(ALB)、空腹血糖(GLU)水平均明显低于对照组(P<0.05)。结论:酒精依赖患者的生化指标存在不同程度的改变,应定期评估并及早干预。
Objective:To investigate changes of serum biochemical indicators of alcohol-dependent patients.Methods:60 al-cohol-dependent patients were used as the alcohol dependence group,while 60 healthy people were set as control group.Their serum biochemical indicators levels were detected by Hitachi 7600 automatic biochemistry analyzer and compared.Results:The levels of K+,Ca2+,P2-,Mg2+,high density lipoprotein(HDL),apolipoprotein A(AproA),total protein(TP),albumin(ALB),and fasting plasma glucose(GLU)of the alcohol dependence were significantly lower than those of the control group(P<0.05);however,the levels of alanine aminotransferase(ALT),aspartate aminotransferase(AST),alkaline phosphatase(ALP),glutamyl transpeptidase(GGT),creatine kinase(CK),lactate dehydrogenase(LDH),total cholesterol(TC),triglyceride(TG),low density lipoprotein(LDL)and apolipoprotein B(AproB)was significantly higher than those of the control group(P<0.05).Conclusions:There are va-rying degrees of changes in the levels of the serum biochemical indicators of the alcohol-dependent patients,which should be measured periodically and cured earlier.
作者
郭月锋
吴强
连卓
GUO Yuefeng;WU Qiang;LIAN Zhuo(The Clinical Laboratory of the 5th People's Hospital of Luoyang,Luoyang Henan 471000,China)
出处
《中国民康医学》
2018年第4期4-5,13,共3页
Medical Journal of Chinese People’s Health
关键词
酒精依赖患者
生化指标
Alcohol-dependent patient
Biochemical indicator
