摘要
目的探讨分析先兆流产与血清糖类抗原(CA125)、人绒毛膜促性腺激素(β-hCG)水平的相关性。方法选择2016年4月~2017年12月我院收治的24例先兆流产孕妇为观察组研究对象,选取同期24例正常妊娠孕妇为对照组研究对象。使用电化学发光免疫法检测两组孕妇血清CA125和β-hCG水平。比较两组孕妇血清CA125、β-hCG水平,并分析先兆流产与血清CA125和β-hCG水平的相关性。结果观察组孕妇血清CA125水平为(41.32±3.98)IU/ml,明显高于对照组[(23.84±3.25)IU/ml],差异有统计学意义(P<0.05);观察组孕妇的血清β-hCG水平为(10631.46±2024.68)mIU/ml,明显低于对照组[(18 224.36±7135.57)IU/ml],差异有统计学意义(P<0.05);先兆流产与血清CA125水平和β-hCG水平具有一定的相关性(P<0.05)。结论先兆流产孕妇的血清CA125水平更高,β-hCG水平明显降低,先兆流产与CA125、β-hCG水平具有相关性,可为临床治疗提供依据。
Objective To investigate the correlation between premonitory abortion and serum CA125 andβ-hCG levels.Methods Altogether 24 cases of premonitory abortion patients who were treated in our hospital from April 2016 to December 2017 were selected as the observation group;while,24 normal pregnant women who were treated in our hospital in the same period were selected as the control group.The serum CA125 andβ-hCG levels of two groups were detected by using electrochemiluminescence immunoassay(ECLIA)and compared;and the correlation between premonitory abortion and serum CA125 andβ-hCG levels was analyzed.Results The serum CA125 level of the observation group was(41.32±3.98)IU/ml,obviously higher than that of control group(23.84±3.25)IU/ml,with statistically significant difference(P<0.05);the serumβ-hCG level of observation group was(10631.46±2024.68)mIU/ml,significantly lower than that of control group([18224.36±7135.57]IU/ml),with statistically significant difference(P<0.05);premonitory abortion and serum CA125 andβ-hCG levels were correlated to a certain degree(P<0.05).Conclusion Pregnant women with premonitory abortion have higher serum CA125 level and significantly lowerβ-hCG level.Premonitory abortion is correlated with serum CA125 andβ-hCG levels,which can provide a basis for clinical treatment.
作者
陈小媚
吕红蕊
江燕
CHEN Xiao-mei;LYU Hong-rui;JIANG Yan(Department of Gynecology and Obstetrics,Guangdong Nongken Central Hospital,Guangdong Province,Zhanjiang 524000,China)
出处
《中国当代医药》
2018年第8期83-85,共3页
China Modern Medicine
