摘要
目的观察米索前列醇联合缩宫素预防自然分娩后产后出血的效果。方法选取2015年2月至2016年2月于本院就诊的自然分娩产妇114例,采用随机数字表法将其分为观察组与对照组,各57例。对照组使用缩宫素预防,观察组使用米索前列醇联合缩宫素预防。对比两组临床指标、出血情况及不良反应发生情况。结果观察组产后出血发生率低于对照组,产后2 h出血量及产后24 h出血量均低于对照组(P<0.05);产后24 h,两组红细胞比容及血红蛋白水平均低于产前,且观察组明显高于对照组(P<0.05);产后24 h,对照组收缩压升高,观察组收缩压降低,且对照组明显高于观察组(P<0.05);两组的不良反应总发生率比较,差异无统计学意义(P>0.05)。结论米索前列醇联合缩宫素预防自然分娩后产后出血疗效确切,可有效减少产妇出血量,降低产后出血发生率,且其对产妇血压影响较小,有助于减少血红蛋白丢失,安全性较好。
Objective To observe the effect of misoprostol and oxytocin in prevention of postpartum hemorrhage after natural delivery.Methods A total of 114 pregnant women with natural delivery in our hospital from February 2015 to February 2016 were selected and divided into observation group and control group,with 57 cases in each group.The control group was given oxytocin,while the observation group was given misoprostol and oxytocin.The clinical indexes,hemorrhage and adverse reactions were compared between the two groups.Results The incidence of postpartum hemorrhage in the observation group was lower than that of the control group,the postpartum 2 h and 24 h hemorrhage volume in the observation group were lower than those in the control group(P<0.05).At postpartum 24 h,the diastolic pressure,hematocrit and hemoglobin levels in the two groups decreased,and those of the observation group were higher than the control group(P<0.05).At postpartum 24 h,the systolic pressure level of the control group increased,and that of the observation group decreased,while that of the control group were higher than the observation group(P<0.05).There was no statistical difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Misoprostol combined with oxytocin in prevention of postpartum hemorrhage after natural delivery is effective,it can reduce hemorrhage volume,decrease the incidence of postpartum hemorrhage,reduce the loss of hemoglobin,has less effect on blood pressure,with better safety.
作者
赵喜迎
ZHAO Xi-ying(Traditional Chinese Medicine Hospital of Chang'an District,Xi'an 710000,China)
出处
《临床医学研究与实践》
2018年第11期138-139,共2页
Clinical Research and Practice
关键词
自然分娩
产后出血
米索前列醇
缩宫素
natural delivery
postpartum hemorrhage
misoprostol
oxytocin
