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肝脏肿瘤患者射频消融术治疗后肝内感染的发生及其影响因素研究 被引量:5

Study on the Incidence and Influencing Factors of Intrahepatic Infection after Radiofrequency Ablation in Patients with Liver Tumors
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摘要 目的:探讨肝脏肿瘤患者接受射频消融术治疗后肝内感染的影响因素。方法:选取本院2013年3月至2017年1月期间本院所收治肝内肿瘤患者140例,均接受射频消融术治疗,对患者术后肝内感染的发生情况进行观察记录,对此类患者射频消融术后发生肝内感染的相关影响因素进行统计分析。结果:单因素分析显示,肿瘤类型、肿瘤个数、腹部手术类型、RFA方式均同肝脏肿瘤患者RFA术后发生肝内感染密切相关(P<0.05),年龄、性别、Child-Pug分级、是否接受抗菌预防治疗均同肝脏肿瘤RFA术后发生肝内感染无明显相关性(P>0.05);多因素分析显示,肿瘤类型、肿瘤个数、腹部手术类型、RFA方式均是影响此类患者RFA治疗后发生肝内感染的关键因素(P<0.05)。结论:肿瘤类型、肿瘤数目、既往腹部手术史、RFA治疗方式均是影响肝脏肿瘤患者在射频消融术后发生肝内感染的关键因素,在对此类患者进行RFA治疗时,应加强术前评估,必要时可给予患者术前预防性抗感染治疗,以降低术后肝内感染发生风险,改善患者预后。 Objective:To investigate the related factors of liver infection after radiofrequency ablation in patients with liver cancer.Methods:140 cases of intrahepatic tumors in our hospital from March 2013 to January 2017 were selected and treated by radiofrequency catheter ablation.The incidence of postoperative intrahepatic infection was observed and recorded.The radiofrequency The incidence of intrahepatic infection after ablation related factors were statistically analyzed.Results:Univariate analysis showed that the type of tumor,the number of tumors,the type of abdominal surgery and RFA were closely related to the occurrence of intrahepatic infection after RFA in patients with liver cancer(P<0.05),age,gender,Child-Pug grade,There was no significant correlation between antimicrobial prophylaxis and intrahepatic infection after hepatic tumor RFA(P>0.05).Multivariate analysis showed that the type of tumor,the number of tumors,the type of abdominal surgery and the RFA method all affected the RFA treatment After the occurrence of intrahepatic infection of the key factors(P<0.05).Conclusion:The type of tumor,the number of tumors,the history of previous abdominal surgery,and the modalities of RFA are the key factors that influence the development of intrahepatic infection in patients with hepatic tumors after radiofrequency ablation.In patients undergoing RFA,preoperative evaluation should be strengthened and necessary Preoperative anti-infective therapy can be given to patients in order to reduce the risk of postoperative intrahepatic infection,improve patient prognosis.
作者 吴逢清 汪秀云 WU Fengqing;WANG Xiuyun(West China Hospital of Sichuan University,Sichuan Chengdu 610041,China)
出处 《河北医学》 CAS 2018年第4期588-591,共4页 Hebei Medicine
基金 四川省科技厅科技支撑计划 (编号:2012SZ00356)
关键词 肝内肿瘤 射频消融术 肝内感染 Intrahepatic tumor Radiofrequency ablation Intrahepatic infection
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