摘要
目的:探讨孕中期唐氏筛查与产前诊断对预防出生缺陷的价值。方法:收治孕妇8 500例,均给予唐氏筛查,对风险率进行计算,针对高风险孕妇给予羊膜腔穿刺和羊水细胞培养核型分析。结果:唐氏筛查阳性率6.98%;三体高风险阳性率0.98%;神经管缺陷高风险阳性率2.04%。结论:采用唐氏筛查能对不良妊娠和异常胎儿进行有效预测,是产前诊断的一个主要环节,是开展羊膜腔穿刺的主要依据之一,在产前诊断中羊水细胞染色体核型分析的作用非常重要。
Objective:To explore the value of down screening and prenatal diagnosis for the prevention of birth defects in the middle of the pregnancy.Methods:8500 pregnant women were selected.All of them were screened by Down's test and the risk rate was calculated,and the amniocentesis and amniotic fluid cell culture karyotype analysis were performed for high-risk pregnant women.Results:The positive rate of down screening was 6.98%;the positive rate of the high risk of trisomy was 0.98%;the positive rate of the high risk of neural tube defects was 2.04%.Conclusion:Down's screening is an effective way to predict adverse pregnancy and abnormal fetus.It is a major link in prenatal diagnosis,and is one of the main bases for developing amniocentesis.The role of karyotype analysis in amniotic fluid cell is very important in prenatal diagnosis.
作者
许海燕
Xu Haiyan(The Central Hospital of Hengyang City 421000)
出处
《中国社区医师》
2018年第12期162-163,共2页
Chinese Community Doctors
关键词
孕中期
唐氏筛查
产前诊断
预防
出生缺陷
Middle pregnancy
Down screening
Prenatal diagnosis
Prevention
Birth defect
